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Lyon Cruise Departures

Cruises that depart from Europe: France: Lyon

Cruises that visit Lyon

See all River Cruises that depart from Lyon

Click on a cruise ship itinerary sailing from Lyon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Lyon), please visit: Cruise Search or try our Virtual Cruise Advisor™.


AmaWaterways, AmaCello
AmaCello Cruise Ship7 Night - Flavors of Burgundy
Starting in Lyon, Macon, Tournus, Chalon-sur-Saone, Seurre, Port of Dijon
2027 Sails: May 20, Jul 29, More...
Scenic Luxury Cruises, Scenic Diamond
Scenic Diamond Cruises20 Night - Iconic France
Starting in Lyon, Lyon / Chalon-Sur-Saone, Chalon-Sur-Saone / Tournus Cruising, Tournon, Avignon, Arles, Viviers, Lyon, Lyon / Bordeaux, Bordeaux / Libourne, Libourne / Fort Medoc, Fort Medoc, Fort Medoc / Cadillac, Cadillac / Bordeaux, Bordeaux, Bordeaux / Bourg, Bourg, Bourg / Blaye / Bordeaux, Bordeaux
2027 Sails: May 30, Oct 19, More...
Scenic Luxury Cruises, Scenic Sapphire
Scenic Sapphire Cruises10 Night - Tastes of the South of France - a Wine Cruise
Starting in Lyon, Lyon / Chalon-Sur-Saone, Chalon-Sur-Saone / Tournus Cruising, Tournon, Avignon, Arles, Viviers, Lyon
2027 Sails: May 30, Aug 12, Oct 19, More...
Scenic Luxury Cruises, Scenic Sapphire
Scenic Sapphire Cruises13 Night - Spectacular South of France with London
Starting in Lyon, Lyon / Chalon-Sur-Saone, Chalon-Sur-Saone / Tournus Cruising, Tournon, Avignon, Arles, Viviers, Lyon, Lyon / London, London
2027 Sails: May 30, More...
Scenic Luxury Cruises, Scenic Sapphire
Scenic Sapphire Cruises7 Night - Idyllic Rhone
Starting in Lyon, Macon, Vienne, Viviers / Avignon, Avignon, Arles, Tarascon / Marseille
2027 Sails: Jul 9, Aug 22, Sep 25, More...
Scenic Luxury Cruises, Scenic Sapphire
Scenic Sapphire Cruises10 Night - Idyllic Rhone with French Riviera
Starting in Lyon, Macon, Vienne, Viviers / Avignon, Avignon, Arles, Tarascon / Nice, Nice
2027 Sails: Aug 22, More...
Scenic Luxury Cruises, Scenic Sapphire
Scenic Sapphire Cruises13 Night - Spectacular South of France with London
Starting in Lyon, Lyon / Chalon-Sur-Saone, Chalon-Sur-Saone / Tournus, Tournon, Avignon, Arles, Viviers, Lyon, Lyon / London, London
2027 Sails: Sep 15, More...

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Lyon Cruise Departures