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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Costa Cruise Lines, Costa Fortuna
Costa Fortuna Cruise Ship7 Night - Eastern Mediterranean from Istanbul
Starting in Istanbul, Izmir, Santorini, Mykonos, Volos, Athens (Piraeus), Istanbul
2026 Sails: May 24, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna Cruise Ship7 Night - Eastern Mediterranean from Istanbul
Starting in Istanbul, Izmir, Volos, Mykonos, Santorini, Athens (Piraeus), Istanbul
2026 Sails: May 31, More...
Seven Seas Splendor Cruises10 Night - Marvels of Antiquity
Starting in Istanbul, Bozcaada, Kusadasi, Cruising the Mediterranean Sea, Alexandria EG, Limassol, Rhodes, Santorini, Cruising the Aegean Sea, Athens (Piraeus)
2026 Sails: Jun 3, More...
NCL Norwegian Viva Cruises10 Night - Greek Isles & Italy
Starting in Istanbul, Turkey, Kusadasi, Turkey, Santorini Island, Greece, Mykonos, Greece, Piraeus / Athens, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Split, Croatia, Venice (Ravenna), Italy
2026 Sails: Jun 5, Jul 31, 2027: Jul 11, Sep 5, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna Cruise Ship7 Night - Eastern Mediterranean from Istanbul
Starting in Istanbul, Mykonos, Heraklion, Rhodes, Santorini, Athens (Piraeus), Istanbul
2026 Sails: Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, More...
Star Clippers, Star Flyer
Star Flyer Cruise Ship7 Night - Yachtsman's Paradise
Starting in Istanbul, Turkey, Dikili, Turkey, Myrina / Limnos, Greece, Ouranoupoli, Greece, Skopelos, Greece, Poros, Greece, Piraeus (Port of Athens), Greece
2026 Sails: Jun 13, More...
Viking Ocean, Viking Vesta
Viking Vesta Cruises21 Night - Adriatic & Mediterranean Sojourn
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Jun 23, More...
Viking Ocean, Viking Vesta
Viking Vesta Cruises14 Night - Ancient Adriatic Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Fusina)
2026 Sails: Jun 23, More...
Viking Ocean, Viking Vesta
Viking Vesta Cruises28 Night - Mediterranean's Iconic Shores
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Jun 23, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra Cruises7 Night - Istanbul to Athens Adventure
Starting in Istanbul, Turkey, Cruise the Dardanelles / Kepez, Turkey, Kusadasi, Turkey, Patmos, Greece, Delos, Greece / Mykonos, Greece, Santorini, Greece, Milos, Greece, Athens (Piraeus), Greece
2026 Sails: Jun 27, More...

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Istanbul Cruise Departures