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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Oceania Vista10 Night - Across the Aegean
Starting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Izmir, Bodrum, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus)
2028 Sails: Mar 21, More...
Viking Ocean, Viking Mars
Viking Mars28 Night - Mediterranean's Iconic Shores
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2028 Sails: Apr 4, More...
Viking Ocean, Viking Mars
Viking Mars21 Night - Adriatic & Mediterranean Sojourn
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Apr 4, More...
Viking Ocean, Viking Mars
Viking Mars14 Night - Ancient Adriatic Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia)
2028 Sails: Apr 4, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2028 Sails: Apr 5, Apr 12, More...
Viking Ocean, Viking Sky
Viking Sky14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Apr 13, More...
Viking Ocean, Viking Sky
Viking Sky7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Apr 13, More...
Viking Ocean, Viking Sky
Viking Sky21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2028 Sails: Apr 13, More...
Seabourn, Seabourn Ovation
Seabourn Ovation7 Night - Yacht Harbors of the Aegean Sea
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece
2028 Sails: May 13, Jul 8, Sep 2, More...
Seabourn, Seabourn Ovation
Seabourn Ovation21 Night - Yacht Harbors of Greece & Dalmatian Gems
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece, Nafplion, Greece, Kotor, Montenegro, Vodice (Sibenik), Croatia, Zadar, Croatia, Koper, Slovenia, Fusina (Venice), Italy, Rovinj, Croatia, Vis Island, Croatia, Valletta, Malta, Lipari, Italy, Sorrento, Italy, Civitavecchia (Rome), Italy
2028 Sails: May 13, Jul 8, More...

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Istanbul Cruise Departures