Istanbul Cruise Departures
Cruises that depart from Mediterranean: Turkey: Istanbul
Cruises that visit Istanbul
See all River Cruises that depart from Istanbul
14 Night - Ancient Adriatic Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia)
2028 Sails: Apr 4, More...
14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Apr 13, More...
7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Apr 13, More...
21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2028 Sails: Apr 13, More...
21 Night - The Best of the Mediterranean
Starting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Heraklion), Greece, Sicily (Messina), Italy, Valletta, Malta, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy, Amalfi Coast (Salerno), Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Corfu, Greece, Katakolon (for Olympia), Greece, Crete (Chania), Greece, Mykonos, Greece, Athens (Piraeus), Greece
2028 Sails: May 5, More...
11 Night - Mediterranean with Greek Isles & Turkey
Starting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Heraklion), Greece, Sicily (Messina), Italy, Valletta, Malta, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2028 Sails: May 5, More...
10 Night - Hellenic-Dalmatian Tapestry
Starting in Istanbul, Bozcaada (Troy), Thessaloniki, Milos, Katakolon, Kotor, Dubrovnik, Croatia, Zadar, Ravenna, Trieste
2028 Sails: May 8, More...
16 Night - Ancient Empires : Turkey, Istanbul & Athens - Cruise & Land Journey
Starting in Istanbul, Cappadocia, Konya, Pamukkale, Pamukkale to Istanbul, Istanbul, Turkey, Cruising the Dardanelles, Turkey / Kepez (Canakkale), Turkey, Dikili (Pergamum), Turkey, Kusadasi (Ephesus), Turkey, Naxos, Greece, Santorini, Greece, Heraklion, Crete, Greece, Adamas Harbour, Milos, Greece, Hydra, Greece, Piraeus (Athens), Greece
2028 Sails: May 11, Aug 7, More...
7 Night - Yacht Harbors of the Aegean Sea
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece
2028 Sails: May 13, Jul 8, Sep 2, More...
21 Night - Yacht Harbors of Greece & Dalmatian Gems
Starting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece, Nafplion, Greece, Kotor, Montenegro, Vodice (Sibenik), Croatia, Zadar, Croatia, Koper, Slovenia, Fusina (Venice), Italy, Rovinj, Croatia, Vis Island, Croatia, Valletta, Malta, Lipari, Italy, Sorrento, Italy, Civitavecchia (Rome), Italy
2028 Sails: May 13, Jul 8, More...
Cruises that depart from Mediterranean: Turkey: Istanbul
Cruises that visit Istanbul
See all River Cruises that depart from Istanbul
Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Ancient Adriatic TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Katakolon (Olympia), Corfu (Kerkyra), Kotor, Dubrovnik, Croatia, Split, Venice (Chioggia)
2028 Sails: Apr 4, More...
14 Night - Ancient Mediterranean AntiquitiesStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Apr 13, More...
7 Night - Ancient Mediterranean TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Apr 13, More...
21 Night - Iconic Mediterranean TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2028 Sails: Apr 13, More...
21 Night - The Best of the MediterraneanStarting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Heraklion), Greece, Sicily (Messina), Italy, Valletta, Malta, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy, Amalfi Coast (Salerno), Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Corfu, Greece, Katakolon (for Olympia), Greece, Crete (Chania), Greece, Mykonos, Greece, Athens (Piraeus), Greece
2028 Sails: May 5, More...
11 Night - Mediterranean with Greek Isles & TurkeyStarting in Istanbul, Turkey, Kusadasi, Turkey (for Ephesus), Rhodes, Greece, Mykonos, Greece, Crete (Heraklion), Greece, Sicily (Messina), Italy, Valletta, Malta, Sicily (Palermo), Italy, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2028 Sails: May 5, More...
10 Night - Hellenic-Dalmatian TapestryStarting in Istanbul, Bozcaada (Troy), Thessaloniki, Milos, Katakolon, Kotor, Dubrovnik, Croatia, Zadar, Ravenna, Trieste
2028 Sails: May 8, More...
16 Night - Ancient Empires : Turkey, Istanbul & Athens - Cruise & Land JourneyStarting in Istanbul, Cappadocia, Konya, Pamukkale, Pamukkale to Istanbul, Istanbul, Turkey, Cruising the Dardanelles, Turkey / Kepez (Canakkale), Turkey, Dikili (Pergamum), Turkey, Kusadasi (Ephesus), Turkey, Naxos, Greece, Santorini, Greece, Heraklion, Crete, Greece, Adamas Harbour, Milos, Greece, Hydra, Greece, Piraeus (Athens), Greece
2028 Sails: May 11, Aug 7, More...
7 Night - Yacht Harbors of the Aegean SeaStarting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece
2028 Sails: May 13, Jul 8, Sep 2, More...
21 Night - Yacht Harbors of Greece & Dalmatian GemsStarting in Istanbul, Turkey, Canakkale, Turkey, Volos, Greece, Patmos, Greece, Symi, Greece, Santorini, Greece, Piraeus (Athens), Greece, Nafplion, Greece, Kotor, Montenegro, Vodice (Sibenik), Croatia, Zadar, Croatia, Koper, Slovenia, Fusina (Venice), Italy, Rovinj, Croatia, Vis Island, Croatia, Valletta, Malta, Lipari, Italy, Sorrento, Italy, Civitavecchia (Rome), Italy
2028 Sails: May 13, Jul 8, More...