Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.

21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Oct 31, More...

MSC Cruises, MSC Splendida

4 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy
2027 Sails: Nov 2, More...

Explora Journeys, EXPLORA V

7 Night - A Journey Through Istanbul's Cosmopolitan Vibrancy to Rome's Timeless Wonders
Starting in Istanbul, Canakkale, Kusadasi, Heraklion, Crete, Siracusa (Sicily), Port of Naples, Civitavecchia (Rome)
2027 Sails: Dec 12, More...

Viking Ocean, Viking Mira

14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Heraklion), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Jan 5, More...

Viking Ocean, Viking Mira

21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Heraklion), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2028 Sails: Jan 5, More...

Viking Ocean, Viking Vela

14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2028 Sails: Jan 25, More...

Viking Ocean, Viking Vela

7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2028 Sails: Jan 25, More...

Viking Ocean, Viking Vela

28 Night - Iberia, the Mediterranean & Aegean
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2028 Sails: Jan 25, More...

Viking Ocean, Viking Vela

Oceania Cruises, Oceania Allura

18 Night - Splendid Southern Seas
Starting in Istanbul, Volos, Athens (Piraeus), Heraklion (Crete), Katakolon, Valletta, Messina (Sicily), Salerno, Rome (Civitavecchia), Salerno, Palermo (Sicily), Golfo Aranci, Ajaccio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Sete, Palma De Mallorca, Barcelona
2028 Sails: Feb 19, More...

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Istanbul Cruise Departures