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Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Amelia Island : Fort Lauderdale : Jacksonville : Miami : Orlando : Palm Beach : Pensacola : Port Canaveral : Port Everglades : Tampa : West Palm Beach

Departing from
Florida
Cruise Specials

MSC Cruises, MSC Divina
MSC Divina13 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain
2026 Sails: Apr 9, More...
MSC Cruises, MSC Divina
MSC Divina15 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain, Cannes (Cote D Azur), France, Civitavecchia (Rome), Italy
2026 Sails: Apr 9, More...
MSC Cruises, MSC Divina
MSC Divina14 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain, Cannes (Cote D Azur), France
2026 Sails: Apr 9, More...
Norwegian Cruise Line, Norwegian Star
Norwegian Star4 Night - Western Caribbean - Tampa
Starting in Tampa, Fl, Cozumel, Mexico, Tampa, Fl
2026 Sails: Apr 9, More...
Royal Caribbean, Explorer of the Seas
Explorer of the Seas4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Apr 9, More...
Royal Caribbean, Freedom of the Seas
Freedom of the Seas4 Night - Caribbean Getwaway Cruise
Starting in Miami, Florida, Nassau, Bahamas, Miami, Florida
2026 Sails: Apr 9, More...
American Cruise Lines, American Liberty
American Liberty8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Apr 10, Apr 24, May 8, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, More...
American Cruise Lines, American Pioneer
American Pioneer15 Night - Grand Florida Coast & Keys Cruise
Starting in Amelia Island, FL, Day of Cruising, Green Cove Springs, FL, St Augustine, FL, Cruising the Tolomato River, Cape Canaveral, FL, Day of Cruising, West Palm Beach, FL, Key Biscayne, FL, Key West, FL, Day of Cruising, Marco Island, FL, Punta Gorda, FL, St Petersburg FL
2026 Sails: Apr 10, Oct 30, More...
Disney Cruise Line, Disney Wish
Disney Wish3 Night - Bahamian Cruise from Port Canaveral
Starting in Port Canaveral, Nassau, Castaway Cay, Port Canaveral
2026 Sails: Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, More...
Holland America, Koningsdam
Koningsdam22 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador, Panama, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Puerto Chiapas, Mexico, Manzanillo, Mexico, Puerto Vallarta, Mexico, San Diego, California, San Francisco, California, Vancouver, BC, CA
2026 Sails: Apr 10, More...

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Florida Cruise Departures