Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Celebrity Cruises, Celebrity Silhouette

8 Night - Aruba, Curacao & Grand Cayman
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Oranjestad, Aruba, Willemstad AN, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...

Celebrity Cruises, Celebrity Summit

5 Night - Bahamas Getaway Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 21, Apr 4, More...

Holland America Line, Nieuw Statendam

14 Night - Western & Eastern Caribbean : Mexico & Bahamas
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Cozumel, Mexico, George Town, Cayman Islands, Montego Bay, Jamaica, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Feb 21, More...

MSC Cruises, MSC Grandiosa

14 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Cozumel, Mexico, George Town, Cayman Islands, Montego Bay, Jamaica, Nassau, Bahamas, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Feb 21, Mar 21, More...

MSC Cruises, MSC World America

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 16, May 30, Jun 27, Sep 5, Sep 19, Oct 3, Oct 17, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 23, Feb 6, Feb 20, Mar 20, More...

Norwegian Cruise Line, Norwegian Encore

7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, Great Stirrup Cay, Bahamas, Miami, Fl
2026 Sails: Feb 21, More...

Princess Cruises, Caribbean Princess

12 Night - Southern Caribbean with Panama
Starting in Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Falmouth, Jamaica, Limon, Costa Rica, Colon, Panama, Aruba, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...

Princess Cruises, Star Princess

7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Belize City, Belize, Roatan (Mahogany Bay, Honduras), Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...

Regent Seven Seas Cruises, Seven Seas Grandeur

7 Night - Secret Shores & Cultural Gems
Starting in Miami, Cruising the Florida Straits, Costa Maya, Mexico, Belize City, Roatan, Cozumel, Mexico, Cruising the Florida Straits, Miami
2026 Sails: Feb 21, More...

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