Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Celebrity Cruises, Celebrity Apex

7 Night - Key West, Bahamas & Grand Turk
Starting in Orlando (Port Canaveral), Fl, Key West, Florida, Bimini, Bahamas, Puerto Plata, Dominican Republic, Grand Turk, Turks and Caicos, Orlando (Port Canaveral), Fl
2026 Sails: Apr 18, More...

Celebrity Cruises, Celebrity Silhouette

8 Night - Aruba, Curacao & Bonaire
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Oranjestad, Aruba, Kralendijk, Bonaire, Fort Lauderdale, Florida
2026 Sails: Apr 18, Nov 21, Dec 19, 2027: Jan 16, More...

Disney Cruise Line, Disney Treasure

7 Night - Western Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Castaway Cay, Port Canaveral
2026 Sails: Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, 2027: Apr 3, Apr 17, May 1, May 15, May 29, More...

Holland America, Zuiderdam

14 Night - Atlantic Seaboard & Colonial New England : Quebec City
Starting in Miami, Florida, Norfolk, Virginia, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Halifax, Nova Scotia, Canada, Sydney NS, Nova Scotia, Canada, Charlottetown, Prince Edward Island, Canada, Cruising Gulf of St Lawrence, Saint Lawrence River Cruising, Quebec City, Quebec, Canada
2026 Sails: Apr 18, More...

MSC Cruises, MSC Grandiosa

14 Night - Msc Grand Voyages
Starting in Port Canaveral (Orlando), Florida, Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal, Barcelona, Spain
2026 Sails: Apr 18, More...

MSC Cruises, MSC Grandiosa

11 Night - Msc Grand Voyages
Starting in Port Canaveral (Orlando), Florida, Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal
2026 Sails: Apr 18, More...

MSC Cruises, MSC World America

7 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, Oct 31, Nov 14, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Mar 6, Mar 20, More...

Royal Caribbean, Explorer of the Seas

5 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Cozumel, Mexico, Puerto Costa Maya, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Apr 18, More...

Royal Caribbean, Freedom of the Seas

5 Night - Caribbean Getaway Cruise
Starting in Miami, Florida, Nassau, Bahamas, Grand Turk, Turks and Caicos, Miami, Florida
2026 Sails: Apr 18, More...

Royal Caribbean, Grandeur of the Seas

5 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Tampa, Florida
2026 Sails: Apr 18, More...

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