Florida Cruise Departures

Cruises that depart from North America: United States: Florida

Cruises that visit Florida

See all River Cruises that depart from Florida

Click on a cruise ship itinerary sailing from Florida (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Florida), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Disney Cruise Line, Disney Treasure

7 Night - Western Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Castaway Cay, Port Canaveral
2026 Sails: Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, More...

Holland America Line, Koningsdam

11 Night - Eastern Caribbean : Windward & Leeward Islands
Starting in Fort Lauderdale, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 24, More...

Holland America Line, Koningsdam

21 Night - Eastern Caribbean : Leeward & U.S. Virgin Islands
Starting in Fort Lauderdale, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, St Thomas, US Virgin Islands, St Johns AG, Antigua, Basseterre, St Kitts and Nevis, Philipsburg, Sint Maarten, San Juan, Puerto Rico, Fort Lauderdale, Florida
2026 Sails: Jan 24, More...

Holland America Line, Zuiderdam

22 Night - Eastern Caribbean & Panama Canal
Starting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 24, More...

Holland America Line, Zuiderdam

7 Night - Eastern Caribbean : Amber Cove & Bahamas
Starting in Miami, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Miami, Florida
2026 Sails: Jan 24, Apr 4, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Jan 24, Jan 31, More...

MSC Cruises, MSC World America

7 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 22, Sep 19, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 23, More...

MSC Cruises, MSC World America

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Roatan Island, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Jan 24, More...

Norwegian Cruise Line, Norwegian Encore

7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 24, More...

Royal Caribbean International, Explorer of the Seas

5 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Cozumel, Mexico, Puerto Costa Maya, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Jan 24, Mar 7, Apr 4, Apr 18, More...

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