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Czech Republic Cruise Departures

Cruises that depart from Europe: Czech Republic

Cruises that visit Czech Republic

See all River Cruises that depart from Czech Republic

Click on a cruise ship itinerary sailing from Czech Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Czech Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Prague


Scenic Luxury, Scenic Jade
Scenic Jade12 Night - Danube in Depth with Prague
Starting in Prague, Prague / Nuremberg, Nuremberg, Regensburg, Passau, Linz, Durnstein / Krems, Vienna, Vienna / Bratislava, Budapest
2026 Sails: Nov 10, More...
AmaWaterways Tours, AmaSonata Tours
AmaSonata Tours10 Night - Romantic Danube (Taste of Christmas) with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Nov 15, More...
AmaWaterways Tours, AmaLea Tours
AmaLea Tours10 Night - Romantic Danube (Taste of Christmas) with Prague Pre-Cruise
Starting in Prague, Regensburg, Villany, Passau, Linz, Weissenkirchen, Vienna, Bratislava, Budapest
2026 Sails: Nov 18, More...
Emerald Cruises, Emerald Luna
Emerald Luna20 Night - Prague to Paris & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 21, More...
Emerald Cruises, Emerald Luna
Emerald Luna17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 21, 2027: Nov 19, More...
AmaWaterways Tours, AmaReina Tours
AmaReina Tours10 Night - Iconic Christmas Markets with Prague Pre-Cruise
Starting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 22, 2027: Dec 12, More...
Emerald Cruises, Emerald Astra
Emerald Astra8 Night - Prague to Budapest & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...
Emerald Cruises, Emerald Astra
Emerald Astra6 Night - Prague & Christmas Time On the Danube
Starting in Prague, Prague / Vienna, Vienna, Bratislava, Budapest
2026 Sails: Nov 26, More...
AmaWaterways Tours, AmaSonata Tours
AmaSonata Tours10 Night - Iconic Christmas Markets with Prague Pre-Cruise
Starting in Prague, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Nov 29, Dec 13, 2027: Dec 5, More...
Avalon Waterways Tours, Avalon Imagery II Tours
Avalon Imagery II Tours7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...

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Czech Republic Cruise Departures