Cape Town Cruise Departures
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
33 Night - World Cruise Segment - Cape Town to London (Dover)
Starting in Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England
2026 Sails: Jun 1, More...
24 Night - West Africa Passage
Starting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Abidjan, Cruising the Atlantic Ocean, Banjul, Dakar, Cruising the Atlantic Ocean, Mindelo (Porto Grande), Cruising the Atlantic Ocean, Arrecife (Lanzarote), Agadir, Cruising the Atlantic Ocean, Cruising the Mediterranean Sea, Barcelona
2026 Sails: Jun 11, More...
12 Night - Iconic Africa with Cruise and Land Package : in Cape Town, Wildlife Cruise, in Victoria Falls, Johannesburg and at Tented Safari Lodge in Greater Kruger National Park
Starting in Cape Town, Victoria Falls, Johannesburg, Kruger Park
2026 Sails: Aug 25, Sep 8, Sep 22, Oct 6, Oct 13, 2027: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Jul 6, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 23, More...11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria Falls
Starting in Cape Town, Victoria Falls
2026 Sails: Aug 25, Sep 8, Sep 22, Oct 6, Oct 13, More...
20 Night - South Atlantic Cruise : from South Africa to Antarctica
Starting in Cape Town, Tristan da Cunha, South Georgia, Antarctic Peninsula, Ushuaia
2026 Sails: Oct 23, More...
22 Night - Cape Town to Mumbai
Starting in Cape Town, Port Elizabeth ZA, East London, Durban, Pointe Des Galets, Port Louis, Mahe, Cochin, New Mangalore, Mumbai
2026 Sails: Nov 10, More...
15 Night - Madagascar Marvels
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis
2027 Sails: Feb 1, More...61 Night - Indian Ocean Odyssey
Starting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis, Cruising the Indian Ocean, Praslin (La Digue), Cruising the Indian Ocean, Male, Cruising the Arabian Sea, Muscat, Cruising the Gulf of Oman, Dubai, Doha, Abu Dhabi, Cruising the Gulf of Oman, Muscat, Cruising the Gulf of Oman, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Aqaba, Luxor (Safaga), Suez Canal (Transit), Jerusalem (Haifa), Cruising the Mediterranean Sea, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Portofino, Cannes, Cruising the Mediterranean Sea, Mahon, Minorca, Palma De Mallorca, Ibiza, Cruising the Balearic Sea, Valencia, Barcelona
2027 Sails: Feb 1, More...
24 Night - Gold & Ivory Coasts
Starting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2027 Sails: Feb 7, More...11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria Falls
Starting in Cape Town, Victoria Falls, Johannesburg
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Jul 6, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 23, More...
Cruises that depart from Africa: South Africa: Cape Town
Cruises that visit Cape Town
See all River Cruises that depart from Cape Town
Click on a cruise ship itinerary sailing from Cape Town (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cape Town), please visit: Cruise Search or try our Virtual Cruise Advisor™.
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33 Night - World Cruise Segment - Cape Town to London (Dover)Starting in Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England
2026 Sails: Jun 1, More...
24 Night - West Africa PassageStarting in Cape Town, Cruising the Atlantic Ocean, Walvis Bay, Cruising the Atlantic Ocean, Sao Tome, Cruising the Gulf of Guinea, Lome, Takoradi, Abidjan, Cruising the Atlantic Ocean, Banjul, Dakar, Cruising the Atlantic Ocean, Mindelo (Porto Grande), Cruising the Atlantic Ocean, Arrecife (Lanzarote), Agadir, Cruising the Atlantic Ocean, Cruising the Mediterranean Sea, Barcelona
2026 Sails: Jun 11, More...
12 Night - Iconic Africa with Cruise and Land Package : in Cape Town, Wildlife Cruise, in Victoria Falls, Johannesburg and at Tented Safari Lodge in Greater Kruger National ParkStarting in Cape Town, Victoria Falls, Johannesburg, Kruger Park
2026 Sails: Aug 25, Sep 8, Sep 22, Oct 6, Oct 13, 2027: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Jul 6, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 23, More...
11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria FallsStarting in Cape Town, Victoria Falls
2026 Sails: Aug 25, Sep 8, Sep 22, Oct 6, Oct 13, More...
20 Night - South Atlantic Cruise : from South Africa to AntarcticaStarting in Cape Town, Tristan da Cunha, South Georgia, Antarctic Peninsula, Ushuaia
2026 Sails: Oct 23, More...
22 Night - Cape Town to MumbaiStarting in Cape Town, Port Elizabeth ZA, East London, Durban, Pointe Des Galets, Port Louis, Mahe, Cochin, New Mangalore, Mumbai
2026 Sails: Nov 10, More...
15 Night - Madagascar MarvelsStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis
2027 Sails: Feb 1, More...
61 Night - Indian Ocean OdysseyStarting in Cape Town, Cruising the Indian Ocean, Port Elizabeth ZA, Cruising the Indian Ocean, Durban, Cruising the Indian Ocean, Cruising the Mozambique Channel, Mayotte, Nosy Be, Antsiranana, Cruising the Indian Ocean, Port Louis, Cruising the Indian Ocean, Praslin (La Digue), Cruising the Indian Ocean, Male, Cruising the Arabian Sea, Muscat, Cruising the Gulf of Oman, Dubai, Doha, Abu Dhabi, Cruising the Gulf of Oman, Muscat, Cruising the Gulf of Oman, Cruising the Arabian Sea, Cruising the Gulf of Aden, Cruising the Red Sea, Jeddah, Cruising the Red Sea, Aqaba, Luxor (Safaga), Suez Canal (Transit), Jerusalem (Haifa), Cruising the Mediterranean Sea, Athens (Piraeus), Cruising the Mediterranean Sea, Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Portofino, Cannes, Cruising the Mediterranean Sea, Mahon, Minorca, Palma De Mallorca, Ibiza, Cruising the Balearic Sea, Valencia, Barcelona
2027 Sails: Feb 1, More...
24 Night - Gold & Ivory CoastsStarting in Cape Town, Luderitz, Walvis Bay, Sao Tome, Lome, Sekondi / Takoradi, Abidjan, Banjul, Dakar, Mindelo (Sao Vicente), Arrecife (Lanzarote), Agadir, Lisbon
2027 Sails: Feb 7, More...
11 Night - from the Cape to the Falls with Cruise and Land Package : in Cape Town, Wildlife Cruise and in Victoria FallsStarting in Cape Town, Victoria Falls, Johannesburg
2027 Sails: Mar 9, Mar 23, Mar 30, Apr 6, Apr 20, Apr 27, May 4, May 18, May 25, Jun 15, Jun 22, Jul 6, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 23, More...
