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California Cruise Departures

Cruises that depart from North America: United States: California

Cruises that visit California

Click on a cruise ship itinerary sailing from California (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just California), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Long Beach : Los Angeles : San Diego : San Francisco

Departing from
California
Cruise Specials

Royal Caribbean, Serenade of the Seas
Serenade of the Seas4 Night - Catalina & Ensenada Cruise
Starting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2026 Sails: Oct 11, Nov 29, Dec 6, More...
Royal Caribbean, Ovation Of The Seas
Ovation Of The Seas4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 12, Oct 19, Oct 26, Nov 2, Nov 9, Nov 16, Nov 23, Nov 30, Dec 14, More...
Norwegian Cruise Line, Norwegian Bliss
Norwegian Bliss16 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl
2026 Sails: Oct 13, More...
Norwegian Cruise Line, Norwegian Bliss
Norwegian Bliss19 Night - Repo - Panama Canal
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Falmouth, Jamaica, Miami, Fl, New York City, Ny
2026 Sails: Oct 13, More...
Princess Cruises, Ruby Princess
Ruby Princess10 Night - Mexican Riviera Princess Players Invitational
Starting in San Francisco, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Oct 13, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas3 Night - Ensenada Cruise
Starting in San Diego, California, Ensenada, Mexico, San Diego, California
2026 Sails: Oct 15, More...
Emerald Princess16 Night - Hawaiian Islands
Starting in Los Angeles, California, Hilo, Hawaii, Kahului, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 16, More...
Royal Caribbean, Voyager of the Seas
Voyager of the Seas6 Night - Cabo Overnight & Ensenada
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 16, Oct 30, More...
Virgin Voyages, Brilliant Lady
Brilliant Lady7 Night - Mexican Riviera Halloween Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Oct 17, More...
Disney Cruise Line, Disney Wonder
Disney Wonder4 Night - Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2026 Sails: Oct 18, Nov 9, 2027: Jan 3, Jan 25, Feb 22, Mar 29, Apr 19, More...

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California Cruise Departures