North America River Cruises
River Cruises that visit North America
River Cruises by region
See all North America Cruises
River cruises by river name
Related areas: Canada : United States
8 Night - Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 3, Jul 17, 2027: Jul 2, Jul 16, Jul 30, 2028: Jul 15, Jul 29, More...
8 Night - Upper Mississippi River Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
14 Night - America's Great River
Starting in St Paul, Minnesota, Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Quad Cities, Iowa, Burlington, Iowa, Hannibal, Missouri, St Louis, Missouri, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jul 4, More...
7 Night - New England Islands Cruise
Starting in Providence, RI, New Bedford, MA, Nantucket Island, MA, Marthas Vineyard, MA, Block Island, RI, Newport, Ri, Bristol, RI, Providence, RI
2026 Sails: Jul 5, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, More...
7 Night - Yankee Seaports Cruise
Starting in Boston, Ma, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2026 Sails: Jul 7, Sep 15, More...
8 Night - Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 10, Jul 24, Aug 7, 2027: Jul 16, Jul 30, Aug 13, 2028: Jul 15, Jul 29, Aug 12, More...8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 10, Jul 24, 2027: Jul 9, Jul 23, Aug 6, 2028: Jul 22, Aug 5, More...8 Night - Upper Mississippi River Cruise
Starting in St Louis, MO / Alton, IL, Cruising the Mississippi River, Hannibal, MO, Day of Cruising, Muscatine, IA, Dubuque, IA, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2027: Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, 2028: Jul 8, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2026 Sails: Jul 18, More...
River Cruises that visit North America
River Cruises by region
See all North America Cruises
Click on a cruise ship itinerary in North America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just North America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Canada : United States
8 Night - Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 3, Jul 17, 2027: Jul 2, Jul 16, Jul 30, 2028: Jul 15, Jul 29, More...
8 Night - Upper Mississippi River CruiseStarting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
14 Night - America's Great RiverStarting in St Paul, Minnesota, Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Quad Cities, Iowa, Burlington, Iowa, Hannibal, Missouri, St Louis, Missouri, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jul 4, More...
7 Night - New England Islands CruiseStarting in Providence, RI, New Bedford, MA, Nantucket Island, MA, Marthas Vineyard, MA, Block Island, RI, Newport, Ri, Bristol, RI, Providence, RI
2026 Sails: Jul 5, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, More...
7 Night - Yankee Seaports CruiseStarting in Boston, Ma, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2026 Sails: Jul 7, Sep 15, More...
8 Night - Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 10, Jul 24, Aug 7, 2027: Jul 16, Jul 30, Aug 13, 2028: Jul 15, Jul 29, Aug 12, More...
8 Night - Ohio River CruiseStarting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 10, Jul 24, 2027: Jul 9, Jul 23, Aug 6, 2028: Jul 22, Aug 5, More...
8 Night - Upper Mississippi River CruiseStarting in St Louis, MO / Alton, IL, Cruising the Mississippi River, Hannibal, MO, Day of Cruising, Muscatine, IA, Dubuque, IA, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2027: Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, 2028: Jul 8, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...
21 Night - Mississippi River OdysseyStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2026 Sails: Jul 18, More...
