North America River Cruises
River Cruises that visit North America
River Cruises by region
See all North America Cruises
River cruises by river name
Related areas: Canada : United States
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...
7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA / Houmas House, LA, New Orleans, La
2026 Sails: Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, May 26, Jul 7, Oct 27, Nov 10, 2027: Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Oct 26, Nov 9, 2028: Feb 16, More...7 Night - Gulf Coast Cruise
Starting in Pensacola, FL, Day of Cruising, Mobile, Al, Biloxi, MS, Ocean Springs, MS, Gulfport / Ship Island, MS, New Orleans, La
2026 Sails: Mar 7, Mar 19, More...
8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...8 Night - Southeast Sea Islands Cruise
Starting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Mar 25, Apr 8, Apr 22, May 6, 2027: Mar 26, Apr 9, Apr 23, May 7, 2028: Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, May 6, More...
River Cruises that visit North America
River Cruises by region
See all North America Cruises
Click on a cruise ship itinerary in North America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just North America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Canada : United States
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...
8 Night - Lower Mississippi River CruiseStarting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA / Houmas House, LA, New Orleans, La
2026 Sails: Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, May 26, Jul 7, Oct 27, Nov 10, 2027: Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Oct 26, Nov 9, 2028: Feb 16, More...
7 Night - Gulf Coast CruiseStarting in Pensacola, FL, Day of Cruising, Mobile, Al, Biloxi, MS, Ocean Springs, MS, Gulfport / Ship Island, MS, New Orleans, La
2026 Sails: Mar 7, Mar 19, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Mar 18, Apr 1, Apr 15, Apr 29, 2027: Mar 19, Apr 2, Apr 16, Apr 30, 2028: Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
8 Night - Southeast Sea Islands CruiseStarting in Charleston, SC, Day of Cruising, Beaufort, SC, Hilton Head Island, SC, Savannah, GA, Cruising Intracoastal Waterway, Jekyll Island / St Simons Island, GA, Amelia Island, FL
2026 Sails: Mar 25, Apr 8, Apr 22, May 6, 2027: Mar 26, Apr 9, Apr 23, May 7, 2028: Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, May 6, More...
