Sicily Cruises
Cruises that visit Mediterranean: Italy: Sicily
10 Night - Western Mediterranean : Idyllic Isles & Hidden Gems
Starting in Civitavecchia (Rome), Italy, Salerno, Italy, Palermo, Sicily, Italy, Cagliari, Sardinia, Italy, Palma De Mallorca, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Lisbon, Portugal
2026 Sails: May 24, More...21 Night - Italy, Spain & Malta Collectors Voyage
Starting in Civitavecchia (Rome), Italy, Salerno, Italy, Palermo, Sicily, Italy, Cagliari, Sardinia, Italy, Palma De Mallorca, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Lisbon, Portugal, Cadiz (Seville), Spain, Tangier, Morocco, Valencia, Spain, Valletta, Malta, Cruising Strait of Messina, Passing Isola di Stromboli, Salerno, Italy, Civitavecchia (Rome), Italy
2026 Sails: May 24, More...
7 Night - Italy, France and Spain
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Ajaccio, Corsica, France, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: May 25, More...14 Night - Adriatic and Western Mediterranean
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Ajaccio, Corsica, France, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy
2026 Sails: May 25, More...
7 Night - Mediterranean Island Voyage : Sicily, Sardinia, Corsica, and Elba - with Smithsonian Journeys
Starting in Nice, Portoferraio, Elba, Bonifacio, Corsica, Cagliari, Sardinia, Palermo, Sicily, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: May 25, More...
7 Night - Greek Isles & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Sicily (Messina), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: May 25, Jul 6, Sep 28, More...
10 Night - Around the Boot
Starting in Trieste, Pula / Rovinj, Zadar, Dubrovnik, Croatia, Corfu, Katakolon, Valletta, Catania (Sicily), Amalfi / Positano, Rome (Civitavecchia)
2026 Sails: May 27, More...
24 Night - Best of Greece - Tour 5C
Starting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: May 27, More...17 Night - Best of Greece - Tour 5B
Starting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: May 27, More...10 Night - Best of Greece - Tour 5A
Starting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: May 27, More...
Cruises that visit Mediterranean: Italy: Sicily
Click on a cruise ship itinerary that visits Sicily (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Sicily), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Western Mediterranean : Idyllic Isles & Hidden GemsStarting in Civitavecchia (Rome), Italy, Salerno, Italy, Palermo, Sicily, Italy, Cagliari, Sardinia, Italy, Palma De Mallorca, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Lisbon, Portugal
2026 Sails: May 24, More...
21 Night - Italy, Spain & Malta Collectors VoyageStarting in Civitavecchia (Rome), Italy, Salerno, Italy, Palermo, Sicily, Italy, Cagliari, Sardinia, Italy, Palma De Mallorca, Spain, Alicante, Spain, Gibraltar, Cadiz (Seville), Spain, Lisbon, Portugal, Cadiz (Seville), Spain, Tangier, Morocco, Valencia, Spain, Valletta, Malta, Cruising Strait of Messina, Passing Isola di Stromboli, Salerno, Italy, Civitavecchia (Rome), Italy
2026 Sails: May 24, More...
7 Night - Italy, France and SpainStarting in Barcelona, Spain, Palma De Mallorca, Spain, Ajaccio, Corsica, France, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: May 25, More...
14 Night - Adriatic and Western MediterraneanStarting in Barcelona, Spain, Palma De Mallorca, Spain, Ajaccio, Corsica, France, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy
2026 Sails: May 25, More...
7 Night - Mediterranean Island Voyage : Sicily, Sardinia, Corsica, and Elba - with Smithsonian JourneysStarting in Nice, Portoferraio, Elba, Bonifacio, Corsica, Cagliari, Sardinia, Palermo, Sicily, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: May 25, More...
7 Night - Greek Isles & Italy CruiseStarting in Rome (Civitavecchia), Italy, Naples, Italy, Sicily (Messina), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: May 25, Jul 6, Sep 28, More...
10 Night - Around the BootStarting in Trieste, Pula / Rovinj, Zadar, Dubrovnik, Croatia, Corfu, Katakolon, Valletta, Catania (Sicily), Amalfi / Positano, Rome (Civitavecchia)
2026 Sails: May 27, More...
24 Night - Best of Greece - Tour 5CStarting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: May 27, More...
17 Night - Best of Greece - Tour 5BStarting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: May 27, More...
10 Night - Best of Greece - Tour 5AStarting in Athens (Piraeus), Greece, Delphi, Greece, Kalambaka, Greece, Athens (Piraeus), Greece, Crete (Heraklion), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: May 27, More...
