San Francisco Cruises
Cruises that visit North America: United States: California: San Francisco
Cruises that depart from San Francisco
8 Night - Vancouver Down the Cali Coast
Starting in Vancouver, British Columbia, Canada, Astoria, Oregon, San Francisco, California, Santa Barbara, California, Catalina Island, California, San Diego, California, Los Angeles, California
2026 Sails: Sep 11, More...
6 Night - Pacific Wine Country
Starting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, Los Angeles, California
2026 Sails: Sep 19, More...
22 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 23, More...6 Night - Pacific Wine Country
Starting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California
2026 Sails: Sep 23, More...
6 Night - Coastal Vancouver to Los Angeles
Starting in Vancouver, British Columbia, Victoria CA, Canada, San Francisco, California, Los Angeles, California
2026 Sails: Sep 25, More...
7 Night - Pacific Wine Country
Starting in Vancouver, Canada, San Francisco, California, San Diego, California, Santa Barbara, California, Los Angeles, California
2026 Sails: Sep 26, More...
21 Night - Panama Canal
Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...5 Night - Pacific Coastal Cruise
Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California
2026 Sails: Sep 27, More...
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...7 Night - Pacific Wine Country Magic Castle Conjurer's Cruise
Starting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California
2026 Sails: Sep 27, More...
Cruises that visit North America: United States: California: San Francisco
Cruises that depart from San Francisco
Click on a cruise ship itinerary that visits San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Vancouver Down the Cali CoastStarting in Vancouver, British Columbia, Canada, Astoria, Oregon, San Francisco, California, Santa Barbara, California, Catalina Island, California, San Diego, California, Los Angeles, California
2026 Sails: Sep 11, More...
6 Night - Pacific Wine CountryStarting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, Los Angeles, California
2026 Sails: Sep 19, More...
22 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 23, More...
6 Night - Pacific Wine CountryStarting in Vancouver, Canada, San Francisco, California, San Diego, California, Los Angeles, California
2026 Sails: Sep 23, More...
6 Night - Coastal Vancouver to Los AngelesStarting in Vancouver, British Columbia, Victoria CA, Canada, San Francisco, California, Los Angeles, California
2026 Sails: Sep 25, More...
7 Night - Pacific Wine CountryStarting in Vancouver, Canada, San Francisco, California, San Diego, California, Santa Barbara, California, Los Angeles, California
2026 Sails: Sep 26, More...
21 Night - Panama CanalStarting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
5 Night - Pacific Coastal CruiseStarting in Vancouver, BC, CA, San Francisco, California, San Diego, California
2026 Sails: Sep 27, More...
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
7 Night - Pacific Wine Country Magic Castle Conjurer's CruiseStarting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California
2026 Sails: Sep 27, More...
