San Diego Cruises
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
7 Night - Pacific Wine Country
Starting in Vancouver, Canada, San Francisco, California, Catalina Island, California, San Diego, California, Los Angeles, California
2027 Sails: Sep 25, More...14 Night - Mexican Riviera & Pacific Winecountry
Starting in Vancouver, Canada, San Francisco, California, Catalina Island, California, San Diego, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Sep 25, More...
19 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Huatulco, Mexico, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2027 Sails: Sep 27, More...
21 Night - Panama Canal
Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 2, More...
28 Night - Circle Hawaii, Pacific Coastal & Sea of Cortez
Starting in Vancouver, BC, CA, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Kona, Hawaii, Hilo, Hawaii, Vancouver, BC, CA, San Diego, California, Mazatlan, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 2, More...20 Night - Panama Canal
Starting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 3, More...
11 Night - Mexican Riviera & Pacific Coast
Starting in Vancouver, BC, CA, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 3, More...
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 6, More...7 Night - Pacific Wine Country
Starting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, San Diego, California, Los Angeles, California
2027 Sails: Oct 6, More...
26 Night - Inca Coast : Mexico & Latin America Legendary Voyage
Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile
2027 Sails: Oct 7, More...
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
Click on a cruise ship itinerary that visits San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Pacific Wine CountryStarting in Vancouver, Canada, San Francisco, California, Catalina Island, California, San Diego, California, Los Angeles, California
2027 Sails: Sep 25, More...
14 Night - Mexican Riviera & Pacific WinecountryStarting in Vancouver, Canada, San Francisco, California, Catalina Island, California, San Diego, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Sep 25, More...
19 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Huatulco, Mexico, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2027 Sails: Sep 27, More...
21 Night - Panama CanalStarting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 2, More...
28 Night - Circle Hawaii, Pacific Coastal & Sea of CortezStarting in Vancouver, BC, CA, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Kona, Hawaii, Hilo, Hawaii, Vancouver, BC, CA, San Diego, California, Mazatlan, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 2, More...
20 Night - Panama CanalStarting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 3, More...
11 Night - Mexican Riviera & Pacific CoastStarting in Vancouver, BC, CA, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 3, More...
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 6, More...
7 Night - Pacific Wine CountryStarting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, San Diego, California, Los Angeles, California
2027 Sails: Oct 6, More...
26 Night - Inca Coast : Mexico & Latin America Legendary VoyageStarting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile
2027 Sails: Oct 7, More...
