Portofino Cruises
Cruises that visit Mediterranean: Italy: Portofino
10 Night - Mediterranean
Starting in Marseille (Provence), France, Tarragona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Nov 4, More...
7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona, Palma De Mallorca, Napoli, Civitavecchia (Rome)
2026 Sails: Nov 5, Nov 12, More...8 Night - Mediterranean
Starting in Tarragona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Nov 5, More...
7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Tarragona, Spain
2026 Sails: Nov 5, More...
10 Night - Radiant Rivieras
Starting in Barcelona, Alicante, Ibiza, Palma De Mallorca, Sete, Toulon, Saint-Tropez, Monte Carlo, Portofino, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Nov 5, More...7 Night - Mediterranean
Starting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Tarragona, Spain, Marseille (Provence), France
2026 Sails: Nov 6, More...
8 Night - Mediterranean
Starting in Valencia, Spain, Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain
2026 Sails: Nov 6, Nov 20, More...
6 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, Barcelona, Spain
2026 Sails: Nov 6, More...7 Night - Western Mediterranean from Marseille
Starting in Marseille, Barcelona, Palma De Mallorca, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille
2026 Sails: Nov 7, Nov 14, More...6 Night - Mediterranean
Starting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Nov 7, More...
Cruises that visit Mediterranean: Italy: Portofino
Click on a cruise ship itinerary that visits Portofino (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portofino), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - MediterraneanStarting in Marseille (Provence), France, Tarragona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Nov 4, More...
7 Night - Western Mediterranean from CivitavecchiaStarting in Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona, Palma De Mallorca, Napoli, Civitavecchia (Rome)
2026 Sails: Nov 5, Nov 12, More...
8 Night - MediterraneanStarting in Tarragona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Nov 5, More...
7 Night - MediterraneanStarting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Tarragona, Spain
2026 Sails: Nov 5, More...
Deal link -> Special
10 Night - Radiant RivierasStarting in Barcelona, Alicante, Ibiza, Palma De Mallorca, Sete, Toulon, Saint-Tropez, Monte Carlo, Portofino, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Nov 5, More...
7 Night - MediterraneanStarting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Tarragona, Spain, Marseille (Provence), France
2026 Sails: Nov 6, More...
8 Night - MediterraneanStarting in Valencia, Spain, Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain
2026 Sails: Nov 6, Nov 20, More...
6 Night - MediterraneanStarting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, Barcelona, Spain
2026 Sails: Nov 6, More...
7 Night - Western Mediterranean from MarseilleStarting in Marseille, Barcelona, Palma De Mallorca, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille
2026 Sails: Nov 7, Nov 14, More...
6 Night - MediterraneanStarting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, Barcelona, Spain, Marseille (Provence), France
2026 Sails: Nov 7, More...
