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Portland ME Cruises

Cruises that visit North America: United States: Maine: Portland ME

Cruises that depart from Portland ME

See all River Cruises that visit Portland ME

Click on a cruise ship itinerary that visits Portland ME (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland ME), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Regal Princess Cruise Ship7 Night - Canada & New England with Saint John
Starting in New York City (Manhattan or Brooklyn), New York, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, New York City (Manhattan or Brooklyn), New York
2027 Sails: Oct 30, More...
American Navigator Cruises14 Night - Grand New England Cruise
Starting in Boston, Ma, Portland ME, Bath, ME, Boothbay Harbor, ME, Bar Harbor, Me, Bangor ME, Rockland / Camden, ME, Portsmouth NH, Gloucester, MA, Provincetown, MA, Newport, Ri, Marthas Vineyard, MA, Nantucket Island / Marthas Vineyard, MA, Plymouth, MA, Boston, Ma
2028 Sails: May 6, May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, More...
EXPLORA IV Cruises12 Night - A Grand Journey from North America's Iconic Cities to Canada's Scenic Wilds
Starting in Miami, New York City, Portland ME, Sydney CA, Charlottetown, Prince Edward Island, Iles De La Madeleine, Gaspe, Quebec City
2028 Sails: May 6, More...
Viking Mars Cruises14 Night - Canada & New England Scenic Shores
Starting in Montreal, Quebec, Quebec City, Quebec, Saguenay, Quebec, Sail the Gulf of St Lawrence, Prince Edward Island (Charlottetown), Sail the Nova Scotia Coast, Saint John NB, New Brunswick, Bar Harbor, Maine, Portland ME, Newport, Rhode Island, Sail the Atlantic Ocean, Fort Lauderdale, Florida
2028 Sails: Oct 11, More...


Portland ME Cruises