Mitilini Cruises
Cruises that visit Mediterranean: Greece: Mitilini
21 Night - Grand Adriatic & Aegean
Starting in Trieste, Hvar, Bari, Kotor, Dubrovnik, Croatia, Corfu, Chania (Crete), Rhodes, Santorini, Athens (Piraeus), Mykonos, Ephesus (Kusadasi), Istanbul, Bozcaada (Troy), Mitilini (Lesbos), Izmir, Chios, Kos, Santorini, Athens (Piraeus)
2026 Sails: Jul 7, More...7 Night - Legendary Turkey & Greece
Starting in Istanbul, Bozcaada (Troy), Mitilini (Lesbos), Izmir, Chios, Kos, Santorini, Athens (Piraeus)
2026 Sails: Jul 21, More...
17 Night - Mythic Mediterranean
Starting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus), Chania (Crete), Argostoli (Cephalonia), Corfu, Sarande, Bari, Kotor, Dubrovnik, Croatia
2026 Sails: Jul 31, More...10 Night - Hellenic Explorer
Starting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus)
2026 Sails: Jul 31, More...7 Night - Aegean & Adriatic Treasures
Starting in Istanbul, Mitilini (Lesbos), Izmir, Kotor, Bari, Zadar, Trieste
2026 Sails: Sep 26, More...
7 Night - Ancient Sites & Cities
Starting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Athens (Piraeus), Mitilini (Lesbos), Istanbul
2026 Sails: Nov 5, More...9 Night - Alluring Ancient Ruins
Starting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Milos, Katakolon, Messina (Sicily), Amalfi / Positano, Olbia / Porto Cervo (Sardinia), Rome (Civitavecchia)
2027 Sails: May 15, More...10 Night - Iconic Greek Isles
Starting in Istanbul, Mitilini (Lesbos), Kavala / Philippi, Thessaloniki, Mykonos, Santorini, Agios Nikolaos (Crete), Katakolon, Taormina (Sicily), Amalfi / Positano, Rome (Civitavecchia)
2027 Sails: Jul 9, More...19 Night - Rome, Ruins & Gondola Rides
Starting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Argostoli (Cephalonia), Tirana (Durres), Kotor, Korcula, Ravenna, Venice (Fusina)
2027 Sails: Jul 19, More...10 Night - Aegean & Adriatic Coasts
Starting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Argostoli (Cephalonia), Tirana (Durres), Kotor, Korcula, Ravenna, Venice (Fusina)
2027 Sails: Jul 28, More...
Cruises that visit Mediterranean: Greece: Mitilini
Click on a cruise ship itinerary that visits Mitilini (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mitilini), please visit: Cruise Search or try our Virtual Cruise Advisor™.
21 Night - Grand Adriatic & AegeanStarting in Trieste, Hvar, Bari, Kotor, Dubrovnik, Croatia, Corfu, Chania (Crete), Rhodes, Santorini, Athens (Piraeus), Mykonos, Ephesus (Kusadasi), Istanbul, Bozcaada (Troy), Mitilini (Lesbos), Izmir, Chios, Kos, Santorini, Athens (Piraeus)
2026 Sails: Jul 7, More...
Deal link -> Special
7 Night - Legendary Turkey & GreeceStarting in Istanbul, Bozcaada (Troy), Mitilini (Lesbos), Izmir, Chios, Kos, Santorini, Athens (Piraeus)
2026 Sails: Jul 21, More...
17 Night - Mythic MediterraneanStarting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus), Chania (Crete), Argostoli (Cephalonia), Corfu, Sarande, Bari, Kotor, Dubrovnik, Croatia
2026 Sails: Jul 31, More...
10 Night - Hellenic ExplorerStarting in Istanbul, Canakkale (Troy), Kavala / Philippi, Thessaloniki, Mitilini (Lesbos), Ephesus (Kusadasi), Rhodes, Heraklion (Crete), Santorini, Mykonos, Athens (Piraeus)
2026 Sails: Jul 31, More...
Deal link -> Special
7 Night - Aegean & Adriatic TreasuresStarting in Istanbul, Mitilini (Lesbos), Izmir, Kotor, Bari, Zadar, Trieste
2026 Sails: Sep 26, More...
7 Night - Ancient Sites & CitiesStarting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Athens (Piraeus), Mitilini (Lesbos), Istanbul
2026 Sails: Nov 5, More...
9 Night - Alluring Ancient RuinsStarting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Milos, Katakolon, Messina (Sicily), Amalfi / Positano, Olbia / Porto Cervo (Sardinia), Rome (Civitavecchia)
2027 Sails: May 15, More...
10 Night - Iconic Greek IslesStarting in Istanbul, Mitilini (Lesbos), Kavala / Philippi, Thessaloniki, Mykonos, Santorini, Agios Nikolaos (Crete), Katakolon, Taormina (Sicily), Amalfi / Positano, Rome (Civitavecchia)
2027 Sails: Jul 9, More...
19 Night - Rome, Ruins & Gondola RidesStarting in Rome (Civitavecchia), Salerno, Palermo (Sicily), Catania (Sicily), Zakynthos, Gythion, Mykonos, Volos, Canakkale (Troy), Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Argostoli (Cephalonia), Tirana (Durres), Kotor, Korcula, Ravenna, Venice (Fusina)
2027 Sails: Jul 19, More...
10 Night - Aegean & Adriatic CoastsStarting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Chania (Crete), Argostoli (Cephalonia), Tirana (Durres), Kotor, Korcula, Ravenna, Venice (Fusina)
2027 Sails: Jul 28, More...
