Lesbos Cruises
Cruises that visit Mediterranean: Greece: Lesbos
7 Night - Aegean & Adriatic Treasures
Starting in Istanbul, Mitilini (Lesbos), Izmir, Kotor, Bari, Zadar, Trieste
2026 Sails: Sep 26, More...
14 Night - Acropolis to Amalfi
Starting in Athens (Piraeus), Mykonos, Bozcaada, Istanbul, Mytilini (Lesbos), Kusadasi, Cruising the Mediterranean Sea, Valletta, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Monte Carlo, Cruising the Mediterranean Sea, Barcelona
2026 Sails: Oct 12, More...28 Night - Ruins, Riviera & Rose Sands
Starting in Athens (Piraeus), Mykonos, Bozcaada, Istanbul, Mytilini (Lesbos), Kusadasi, Cruising the Mediterranean Sea, Valletta, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Monte Carlo, Cruising the Mediterranean Sea, Barcelona, Cruising the Mediterranean Sea, Malaga, Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Hamilton, Cruising the Atlantic Ocean, Miami
2026 Sails: Oct 12, More...
12 Night - Beauty Under the Stars
Starting in Valletta, Cruising the Mediterranean Sea, Catania (Sicily), Gallipoli, Dubrovnik, Croatia, Kotor, Katakolon, Cruising the Aegean Sea, Istanbul, Mytilini (Lesbos), Kusadasi, Santorini, Athens (Piraeus)
2026 Sails: Oct 20, More...
7 Night - Ancient Sites & Cities
Starting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Athens (Piraeus), Mitilini (Lesbos), Istanbul
2026 Sails: Nov 5, More...
17 Night - Ancient & Historic Shores
Starting in Venice (Trieste), Split, Dubrovnik, Croatia, Kotor, Cruising the Ionian Sea, Katakolon, Mykonos, Athens (Piraeus), Cruising the Adriatic Sea, Split, Cruising the Ionian Sea, Heraklion (Crete), Mykonos, Kusadasi, Mytilini (Lesbos), Cruising the Aegean Sea, Istanbul
2026 Sails: Nov 10, More...10 Night - Spotlight with Mark Bittman
Starting in Athens (Piraeus), Cruising the Adriatic Sea, Split, Cruising the Ionian Sea, Heraklion (Crete), Mykonos, Kusadasi, Mytilini (Lesbos), Cruising the Aegean Sea, Istanbul
2026 Sails: Nov 17, More...
14 Night - Greece Intensive Combination Cruise : Santorini, Volos & Mykonos
Starting in Athens (Piraeus), Santorini, Agios Nikolaos, (Crete), Rhodes, Cesme, Canakkale (Kepez), Istanbul, Canakkale (Kepez), Mytilene, Lesbos, Thessaloniki, Mykonos, Monemvasia, Nafplio, Athens (Piraeus)
2027 Sails: Apr 24, More...8 Night - Greece Intensive Cruise : Thessaloniki, Mykonos & Athens
Starting in Istanbul, Canakkale (Kepez), Mytilene, Lesbos, Thessaloniki, Mykonos, Monemvasia, Nafplio, Athens (Piraeus)
2027 Sails: Apr 30, More...9 Night - Alluring Ancient Ruins
Starting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Milos, Katakolon, Catania (Sicily), Amalfi / Positano, Olbia / Porto Cervo (Sardinia), Rome (Civitavecchia)
2027 Sails: May 15, More...
Cruises that visit Mediterranean: Greece: Lesbos
Click on a cruise ship itinerary that visits Lesbos (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Lesbos), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Aegean & Adriatic TreasuresStarting in Istanbul, Mitilini (Lesbos), Izmir, Kotor, Bari, Zadar, Trieste
2026 Sails: Sep 26, More...
14 Night - Acropolis to AmalfiStarting in Athens (Piraeus), Mykonos, Bozcaada, Istanbul, Mytilini (Lesbos), Kusadasi, Cruising the Mediterranean Sea, Valletta, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Monte Carlo, Cruising the Mediterranean Sea, Barcelona
2026 Sails: Oct 12, More...
28 Night - Ruins, Riviera & Rose SandsStarting in Athens (Piraeus), Mykonos, Bozcaada, Istanbul, Mytilini (Lesbos), Kusadasi, Cruising the Mediterranean Sea, Valletta, Messina (Sicily), Sorrento / Capri, Rome (Civitavecchia), La Spezia (Cinque Terre), Monte Carlo, Cruising the Mediterranean Sea, Barcelona, Cruising the Mediterranean Sea, Malaga, Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Hamilton, Cruising the Atlantic Ocean, Miami
2026 Sails: Oct 12, More...
12 Night - Beauty Under the StarsStarting in Valletta, Cruising the Mediterranean Sea, Catania (Sicily), Gallipoli, Dubrovnik, Croatia, Kotor, Katakolon, Cruising the Aegean Sea, Istanbul, Mytilini (Lesbos), Kusadasi, Santorini, Athens (Piraeus)
2026 Sails: Oct 20, More...
7 Night - Ancient Sites & CitiesStarting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Athens (Piraeus), Mitilini (Lesbos), Istanbul
2026 Sails: Nov 5, More...
17 Night - Ancient & Historic ShoresStarting in Venice (Trieste), Split, Dubrovnik, Croatia, Kotor, Cruising the Ionian Sea, Katakolon, Mykonos, Athens (Piraeus), Cruising the Adriatic Sea, Split, Cruising the Ionian Sea, Heraklion (Crete), Mykonos, Kusadasi, Mytilini (Lesbos), Cruising the Aegean Sea, Istanbul
2026 Sails: Nov 10, More...
10 Night - Spotlight with Mark BittmanStarting in Athens (Piraeus), Cruising the Adriatic Sea, Split, Cruising the Ionian Sea, Heraklion (Crete), Mykonos, Kusadasi, Mytilini (Lesbos), Cruising the Aegean Sea, Istanbul
2026 Sails: Nov 17, More...
14 Night - Greece Intensive Combination Cruise : Santorini, Volos & MykonosStarting in Athens (Piraeus), Santorini, Agios Nikolaos, (Crete), Rhodes, Cesme, Canakkale (Kepez), Istanbul, Canakkale (Kepez), Mytilene, Lesbos, Thessaloniki, Mykonos, Monemvasia, Nafplio, Athens (Piraeus)
2027 Sails: Apr 24, More...
8 Night - Greece Intensive Cruise : Thessaloniki, Mykonos & AthensStarting in Istanbul, Canakkale (Kepez), Mytilene, Lesbos, Thessaloniki, Mykonos, Monemvasia, Nafplio, Athens (Piraeus)
2027 Sails: Apr 30, More...
9 Night - Alluring Ancient RuinsStarting in Istanbul, Mitilini (Lesbos), Ephesus (Kusadasi), Milos, Katakolon, Catania (Sicily), Amalfi / Positano, Olbia / Porto Cervo (Sardinia), Rome (Civitavecchia)
2027 Sails: May 15, More...
