Great Smoky Mountain National Park Cruises

Cruises that visit North America: United States: Tennessee: Great Smoky Mountain National Park

See all River Cruises that visit Great Smoky Mountain National Park

Click on a cruise ship itinerary that visits Great Smoky Mountain National Park (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Great Smoky Mountain National Park), please visit: Cruise Search or try our Virtual Cruise Advisor™.

American Cruise Lines Cruise Tours, American Symphony Cruise Tours

11 Night - Great Smoky Mountains National Park
Starting in Nashville, TN, Afternoon of Cruising, Cruising Lake Barkley and the Cumberland River, Paducah, KY, Savannah, TN, Florence, AL, Decatur, AL, Chattanooga, TN, Pigeon Forge, TN, Great Smoky Mountain National Park, Knoxville, TN
2026 Sails: Apr 28, May 26, Jun 9, Sep 15, Sep 29, Oct 13, 2027: Apr 27, May 25, Jun 8, Oct 15, More...

American Cruise Lines Cruise Tours, American Symphony Cruise Tours

11 Night - Great Smoky Mountains National Park
Starting in Knoxville, TN, Pigeon Forge, TN, Great Smoky Mountain National Park, Chattanooga, TN, Decatur, AL, Florence, AL, Savannah, TN, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Nashville, TN
2026 Sails: May 2, May 16, May 30, Jun 13, Sep 19, Oct 3, Oct 17, 2027: May 1, May 15, May 29, Jun 12, Oct 5, Oct 19, More...

American Cruise Lines Cruise Tours, American Splendor Cruise Tours

11 Night - Great Smoky Mountains National Park
Starting in Knoxville, TN, Pigeon Forge, TN, Great Smoky Mountain National Park, Chattanooga, TN, Decatur, AL, Florence, AL, Savannah, TN, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Nashville, TN
2026 Sails: Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, More...

Great Smoky Mountain National Park Cruises