Mediterranean Cruises

Cruises that visit the Mediterranean

Cruises by region

See all Mediterranean River Cruises

Click on a cruise ship itinerary in the Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Albania : Algeria : Croatia / Hrvatska : Cyprus : Egypt : Gibraltar : Greece : Israel : Italy : Malta : Monaco : Montenegro : Slovenia : Tunisia : Turkey

Windstar, Wind Surf

10 Night - Sicilian Splendors
Starting in Rome, Syracuse IT, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome
2026 Sails: May 21, More...

Windstar, Wind Surf

13 Night - Historic Harbors of Italy & Beyond
Starting in Rome, Syracuse IT, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome, Porto Venere, Bonifacio, France, Rome
2026 Sails: May 21, More...

Avalon Waterways Tours, Avalon Envision Tours

11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Sep 11, Oct 9, Oct 23, Nov 6, Nov 20, More...

Celebrity Cruises, Celebrity Infinity

8 Night - Best of Greece Cruise
Starting in Athens (Piraeus), Greece, Santorini, Greece, Rhodes, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Thessaloniki, Greece, Athens (Piraeus), Greece
2026 Sails: May 22, More...

Celebrity Cruises, Celebrity Xcel

10 Night - Italy & French Riviera
Starting in Barcelona, Spain, Naples, Italy, Sicily (Messina), Italy, Rome (Civitavecchia), Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Barcelona, Spain
2026 Sails: May 22, Oct 2, More...

Costa Cruise Lines, Costa Fortuna

7 Night - Eastern Mediterranean from Athens (Pireo)
Starting in Athens (Piraeus), Istanbul, Izmir, Santorini, Mykonos, Volos, Athens (Piraeus)
2026 Sails: May 22, More...

Emerald Cruises, Emerald Star

12 Night - Transylvania & Enchantment of Eastern Europe
Starting in Bucharest, Bucharest / Brasov, Brasov, Brasov / Bucharest, Bucharest / Giurgiu, Rousse, Vidin, Donji Milanovac / Golubac, Belgrade, Vukovar, Ordas, Budapest
2026 Sails: May 22, More...

Lindblad Expeditions, National Geographic Orion

12 Night - Mediterranean Wonders : Sicily, Greece, Sardinia and Beyond
Starting in Barcelona, Spain / Embark Ship, Ciutadella de Menorca, At Sea / Bonifacio, Corsica, France, Bonifacio, Golfo Aranci, Sardinia, Italy, At Sea / Aeolian Islands, Taormina, Sicily, Siracusa / At Sea, Corfu, Greece, Cephalonia, Delphi / Corinth Canal, Athens / Disembark Ship
2026 Sails: May 22, 2027: Apr 7, Aug 9, More...

Oceania Cruises, Oceania Nautica

10 Night - Italy & France Spotlight
Starting in Rome (Civitavecchia), Amalfi / Positano, Palermo (Sicily), Olbia / Porto Cervo (Sardinia), Bastia (Corsica), Piombino (Tuscany), Florence / Pisa / Tuscany (Livorno), Nice, Saint-Tropez, Toulon, Barcelona
2026 Sails: May 22, More...

Regent Seven Seas, Seven Seas Splendor

12 Night - Spring in the Aegean
Starting in Istanbul, Cruising the Aegean Sea, Kavala, Thessaloniki, Skiathos, Athens (Piraeus), Mykonos, Heraklion (Crete), Marmaris, Cruising the Aegean Sea, Izmir, Istanbul
2026 Sails: May 22, More...

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