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Switzerland Cruise Departures

Cruises that depart from Europe: Switzerland

Cruises that visit Switzerland

See all River Cruises that depart from Switzerland

Click on a cruise ship itinerary sailing from Switzerland (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Switzerland), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Basel : Geneva : Lucerne : Zurich


Uniworld, S.S. Victoria
S.S. Victoria7 Night - Castles Along the Rhine
Starting in Basel, Basel, Breisach, Strasbourg, Mannheim, Rudesheim, Braubach, Koblenz, Cologne, Cologne, Amsterdam
2026 Sails: Sep 20, Nov 1, More...
Uniworld, S.S. Antoinette
S.S. Antoinette10 Night - Remarkable Rhine & Historic Holland
Starting in Basel, Strasbourg, Speyer (Mannheim), Mainz, Boppard, Boppard, Cologne, Cologne, Arnhem, Rotterdam, Amsterdam
2026 Sails: Sep 21, Oct 11, Oct 31, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II10 Night - The Rhine & Moselle (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Bernkastel, Trier Excursion to Luxembourg, Cochem, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Sep 22, Oct 11, More...
Emerald Cruises, Emerald Astra
Emerald Astra10 Night - Rhine Castles & Moselle Vineyards
Starting in Zurich / Basel (Huningue) Embarkation, Breisach / Colmar, Kehl / Strasbourg, Mainz / Rudesheim, Rudesheim, Bernkastel, Cochem / Koblenz, Koblenz / Bonn, Nijmegen, Dordrecht / Rotterdam, Amsterdam
2026 Sails: Sep 22, More...
Emerald Cruises, Emerald Astra
Emerald Astra12 Night - Rhine Castles & Moselle Vineyards with Amsterdam
Starting in Zurich / Basel (Breisach) Embarkation, Breisach / Colmar, Kehl / Strasbourg, Mainz / Rudesheim, Rudesheim, Bernkastel, Cochem / Koblenz, Koblenz / Bonn, Nijmegen, Dordrecht / Rotterdam, Amsterdam (Zaandam), Amsterdam
2026 Sails: Sep 22, More...
Emerald Cruises, Emerald Astra
Emerald Astra12 Night - Rhine Castles & Moselle Vineyards with Amsterdam
Starting in Basel (Breisach) Embarkation, Breisach / Colmar, Kehl / Strasbourg, Mainz / Rudesheim, Rudesheim, Bernkastel, Cochem / Koblenz, Koblenz / Bonn, Nijmegen, Dordrecht / Rotterdam, Amsterdam (Zaandam), Amsterdam
2026 Sails: Sep 22, More...
Emerald Cruises, Emerald Liberte
Emerald Liberte11 Night - Swiss Mountains, Sensations of Lyon and Provence with Nice
Starting in Geneva / Lausanne, Lausanne, Lausanne / Lyon, Lyon, Macon, Tournon, Viviers, Avignon, Arles, Arles / Nice
2026 Sails: Sep 22, 2027: Apr 20, Jul 13, More...
Emerald Cruises, Emerald Liberte
Emerald Liberte11 Night - Swiss Mountains with Sensations of Lyon and Provence
Starting in Geneva / Lausanne, Lausanne, Lausanne / Lyon, Lyon, Macon, Tournon, Viviers, Avignon, Arles, Arles / Marseille
2026 Sails: Sep 22, More...
Scenic Luxury, Scenic Ruby
Scenic Ruby11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Zurich, Zurich / Lucerne / Bern, Bern / Montreux, Montreux, Montreux / Breisach, Breisach, Rastatt, Rudesheim, Cochem, Bernkastel, Koblenz, Mainz / Frankfurt
2026 Sails: Sep 26, More...
AmaWaterways Tours, AmaCerto Tours
AmaCerto Tours14 Night - Rhine & Moselle Delights with Zurich, Lake Lucerne Pre-Cruise
Starting in Zurich, Basel, Breisach, Strasbourg, Ludwigshafen, Bernkastel, Wasserbillig, Cochem, Cologne, Amsterdam
2026 Sails: Sep 30, 2027: Apr 10, Jun 19, Jul 31, Sep 11, Oct 23, More...

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Switzerland Cruise Departures