Switzerland Cruise Departures

Cruises that depart from Europe: Switzerland

Cruises that visit Switzerland

See all River Cruises that depart from Switzerland

Click on a cruise ship itinerary sailing from Switzerland (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Switzerland), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Basel : Geneva : Lucerne : Zurich

14 Night - Grand Rhine & Dutch Canals
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Rudesheim, Dusseldorf, Utrecht, Amsterdam, Hellevoetsluis, Ghent, Brussels, Antwerp, Dordrecht, Kinderdijk, Amsterdam
2026 Sails: Nov 7, More...

AmaWaterways Tours, AmaCello Tours

13 Night - Essence of Burgundy & Provence (Wine Cruise) with Geneva Pre-Cruise and Nice Post-Cruise
Starting in Geneva, Dijon, Chalon-sur-Saone, Tournus, Lyon, Vienne, Viviers, Avignon, Arles, Nice, Barcelona
2026 Sails: Nov 9, 2027: Nov 8, More...

Avalon Waterways, Avalon Envision

14 Night - Timeless Rivers of Europe : the Rhine and Seine
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Nov 10, More...

AmaWaterways, AmaCerto

7 Night - City Escapes : the Rhine
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Mainz, Cologne, Amsterdam
2026 Sails: Nov 11, More...

AmaWaterways, AmaSiena

7 Night - City Escapes : the Rhine
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Mainz, Cologne, Amsterdam
2026 Sails: Nov 12, 2027: Feb 14, Feb 28, 2028: Feb 13, More...

Scenic Luxury, Scenic Opal

11 Night - Rhine Highlights with Switzerland
Starting in Zurich, Zurich / Lucerne / Bern, Bern / Montreux, Montreux, Montreux / Basel (Huningue), Kehl, Rastatt, Mannheim, Koblenz, Cologne, Amsterdam
2026 Sails: Nov 13, More...

AmaWaterways, AmaViola

7 Night - City Escapes : the Rhine
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Mainz, Cologne, Amsterdam
2026 Sails: Nov 14, More...

AmaWaterways Tours, AmaPrima Tours

11 Night - Enchanting Rhine (Celebration of Wine, Taste of Christmas) with Zurich, Lake Lucerne Pre-Cruise
Starting in Zurich, Breisach, Strasbourg, Ludwigshafen, Lahnstein, Cologne, Utrecht, Amsterdam
2026 Sails: Nov 14, More...

AmaWaterways Tours, AmaVenita Tours

10 Night - Swiss Alps & Rhine Castles (Christmas) with Lake Como Pre-Cruise
Starting in Basel, Strasbourg, Ludwigshafen, Lahnstein, Cologne, Amsterdam
2026 Sails: Nov 14, Nov 28, Dec 12, More...

Scenic Luxury, Scenic Opal

7 Night - Rhine Highlights
Starting in Basel (Huningue), Kehl, Rastatt, Mannheim, Koblenz, Cologne, Amsterdam
2026 Sails: Nov 17, More...

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Switzerland Cruise Departures