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Switzerland Cruise Departures

Cruises that depart from Europe: Switzerland

Cruises that visit Switzerland

See all River Cruises that depart from Switzerland

Click on a cruise ship itinerary sailing from Switzerland (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Switzerland), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Basel : Geneva : Lake Geneva : Lucerne : Zermatt : Zurich


AmaWaterways, AmaVenita
AmaVenita Cruises7 Night - Swiss Alps & Rhine Castles
Starting in Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2025 Sails: Dec 15, 2026: May 19, Jun 2, Jun 16, Jun 30, Jul 14, Jul 28, Aug 11, Aug 25, Sep 22, Oct 6, Oct 20, Nov 17, Dec 1, Dec 15, 2027: Mar 23, May 18, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 7, More...
Avalon Waterways, Avalon View
Avalon View Cruises7 Night - Christmastime On the Romantic Rhine (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2025 Sails: Dec 16, More...
Uniworld Boutique River Cruise Collection, S.S. Elisabeth
S.S. Elisabeth Cruises7 Night - Rhine Holiday Markets
Starting in Basel, Strasbourg, Mannheim (Baden-Baden), Mainz, Rudesheim, Cruising the romantic Rhine River, Koblenz, Cologne
2025 Sails: Dec 16, More...
AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Christmas Markets On the Rhine
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Dusseldorf, Amsterdam
2025 Sails: Dec 17, More...
Avalon Waterways, Avalon Panorama
Avalon Panorama Cruise Ship4 Night - Christmastime in Alsace & Germany (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt (Disembarkation)
2025 Sails: Dec 17, 2026: Nov 29, More...
AmaWaterways Cruise Tours, AmaSerena Cruise Tours
AmaSerena Cruise Tours10 Night - Swiss Alps & Rhine Castles (Festive Delights) with Lake Como Pre-Cruise
Starting in Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2025 Sails: Dec 19, 2026: Nov 21, Dec 19, More...
AmaWaterways Cruise Tours, AmaCerto Cruise Tours
AmaCerto Cruise Tours11 Night - Enchanting Rhine with Zurich, Lucerne Pre-Cruise
Starting in Zurich, Lucerne, Breisach, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Dusseldorf, Amsterdam
2025 Sails: Dec 20, More...
AmaWaterways Cruise Tours, AmaSiena Cruise Tours
AmaSiena Cruise Tours11 Night - Enchanting Rhine with Zurich, Lucerne Pre-Cruise
Starting in Zurich, Lucerne, Breisach, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Dusseldorf, Amsterdam
2025 Sails: Dec 21, More...
AmaWaterways, AmaSerena
AmaSerena Cruises7 Night - Swiss Alps & Rhine Castles
Starting in Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2025 Sails: Dec 22, 2026: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Nov 24, Dec 22, 2027: May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, More...
AmaWaterways, AmaCerto
AmaCerto Cruises7 Night - Enchanting Rhine
Starting in Basel, Breisach, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Dusseldorf, Amsterdam
2025 Sails: Dec 24, More...

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Switzerland Cruise Departures