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Southampton Cruise Departures

Cruises that depart from Europe: United Kingdom: England: Southampton

Cruises that visit Southampton

Click on a cruise ship itinerary sailing from Southampton (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Southampton), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Royal Caribbean, Liberty of the Seas
Liberty of the Seas15 Night - Spain & Portugal Transatlantic
Starting in Southampton, England, Vigo, Spain, Lisbon, Portugal, Madeira (Funchal), Portugal, Galveston, Texas
2026 Sails: Oct 16, More...
Celebrity Cruises, Celebrity Apex
Celebrity Apex13 Night - Portugal & Bermuda Transatlantic
Starting in Southampton, England, Vigo, Spain, Lisbon, Portugal, Ponta Delgada, Azores, Royal Naval Dockyard, Bermuda, Orlando (Port Canaveral), Fl
2026 Sails: Oct 18, More...
Cunard Line, Queen Mary 2
Queen Mary 22 Night - Southampton to Hamburg
Starting in Southampton, England, UK, Hamburg, Germany
2026 Sails: Oct 18, More...
Cunard Line, Queen Mary 2
Queen Mary 25 Night - Hamburg and Zeebrugge Short Break
Starting in Southampton, England, UK, Hamburg, Germany, Zeebrugge (tours to Bruges), Belgium, Southampton, England, UK
2026 Sails: Oct 18, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa5 Night - Northern Europe
Starting in Southampton (London), United Kingdom, Zeebrugge (Bruges), Belgium, Rotterdam (Amsterdam), Netherlands, Cherbourg (Mont Saint-Michel), France, Southampton (London), United Kingdom
2026 Sails: Oct 19, More...
Cunard Line, Queen Mary 2
Queen Mary 27 Night - Abbey Road at Sea
Starting in Southampton, England, UK, New York, NY
2026 Sails: Oct 23, Nov 10, Dec 12, More...
Cunard Line, Queen Mary 2
Queen Mary 214 Night - Roundtrip Transatlantic Crossing
Starting in Southampton, England, UK, New York, NY, Southampton, England, UK
2026 Sails: Oct 23, More...
MSC Cruises, MSC Preziosa
MSC Preziosa7 Night - Northern Europe
Starting in Southampton (London), United Kingdom, Hamburg, Germany, Zeebrugge (Bruges), Belgium, Rotterdam (Amsterdam), Netherlands, Le Havre (Paris), France, Southampton (London), United Kingdom
2026 Sails: Oct 23, 2027: Jan 1, Feb 26, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa7 Night - Northern Europe
Starting in Southampton (London), United Kingdom, La Rochelle, France, Bilbao, Spain, La Coruna (Santiago De Compostela), Spain, Le Havre (Paris), France, Southampton (London), United Kingdom
2026 Sails: Oct 24, More...
Cunard Line, Queen Anne
Queen Anne7 Night - Spain and France
Starting in Southampton, England, UK, Getxo (Tours to Bilbao), Spain, Santander, Spain, Gijon, Spain, Cherbourg, France, Southampton, England, UK
2026 Sails: Oct 25, More...

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Southampton Cruise Departures