Southampton Cruise Departures
Cruises that depart from Europe: United Kingdom: England: Southampton
Cruises that visit Southampton
40 Night - Western Mediterranean from Southampton to Limassol
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol
2026 Sails: Sep 30, More...8 Night - Western Mediterranean from Southampton to Alicante
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante
2026 Sails: Sep 30, More...61 Night - Western Mediterranean from Southampton to Santa Cruz de Tenerife
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife
2026 Sails: Sep 30, More...19 Night - Western Mediterranean from Southampton to Valletta
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta
2026 Sails: Sep 30, More...29 Night - Western Mediterranean from Southampton to Heraklion
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion
2026 Sails: Sep 30, More...50 Night - Western Mediterranean from Southampton to Athens (Piraeus)
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Sep 30, More...71 Night - Cruise Roundtrip from Southampton
Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Sep 30, More...
7 Night - Spain & France Cruise
Starting in Southampton, England, Bordeaux (La Rochelle), France, Bilbao, La Coruna, Spain, Paris (Le Havre), France, Southampton, England
2026 Sails: Oct 3, More...
11 Night - Canaries & Portugal Cruise
Starting in Southampton, England, Porto (Leixoes), Portugal, Lisbon, Portugal, Gran Canaria, Canary Islands, Tenerife, Canary Islands, Madeira (Funchal), Portugal, Vigo, Spain, Southampton, England
2026 Sails: Oct 7, More...
4 Night - Rotterdam and Zeebrugge Short Break
Starting in Southampton, England, UK, Rotterdam, Netherlands, Zeebrugge (tours to Bruges), Belgium, Southampton, England, UK
2026 Sails: Oct 9, More...
Cruises that depart from Europe: United Kingdom: England: Southampton
Cruises that visit Southampton
Click on a cruise ship itinerary sailing from Southampton (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Southampton), please visit: Cruise Search or try our Virtual Cruise Advisor™.
40 Night - Western Mediterranean from Southampton to LimassolStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol
2026 Sails: Sep 30, More...
8 Night - Western Mediterranean from Southampton to AlicanteStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante
2026 Sails: Sep 30, More...
61 Night - Western Mediterranean from Southampton to Santa Cruz de TenerifeStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife
2026 Sails: Sep 30, More...
19 Night - Western Mediterranean from Southampton to VallettaStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta
2026 Sails: Sep 30, More...
29 Night - Western Mediterranean from Southampton to HeraklionStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion
2026 Sails: Sep 30, More...
50 Night - Western Mediterranean from Southampton to Athens (Piraeus)Starting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Sep 30, More...
71 Night - Cruise Roundtrip from SouthamptonStarting in Southampton, Vigo, Cadiz, Malaga, Cartagena ES, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Dubrovnik, Croatia, Split, Koper, Zadar, Cruising Bay of Kotor, Kotor, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Sep 30, More...
7 Night - Spain & France CruiseStarting in Southampton, England, Bordeaux (La Rochelle), France, Bilbao, La Coruna, Spain, Paris (Le Havre), France, Southampton, England
2026 Sails: Oct 3, More...
Deal link -> Special
11 Night - Canaries & Portugal CruiseStarting in Southampton, England, Porto (Leixoes), Portugal, Lisbon, Portugal, Gran Canaria, Canary Islands, Tenerife, Canary Islands, Madeira (Funchal), Portugal, Vigo, Spain, Southampton, England
2026 Sails: Oct 7, More...
4 Night - Rotterdam and Zeebrugge Short BreakStarting in Southampton, England, UK, Rotterdam, Netherlands, Zeebrugge (tours to Bruges), Belgium, Southampton, England, UK
2026 Sails: Oct 9, More...
