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Southampton Cruise Departures

Cruises that depart from Europe: United Kingdom: England: Southampton

Cruises that visit Southampton

Click on a cruise ship itinerary sailing from Southampton (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Southampton), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Silversea, Silver Dawn
Silver Dawn12 Night - Southampton to Lisbon
Starting in Southampton, St Helier, Saint Malo (Brittany), Bordeaux, Bilbao, Santander, Vigo (Galicia), Oporto (Leixoes), Lisbon
2026 Sails: Sep 19, More...
Cunard Line, Queen Anne
Queen Anne9 Night - Spain and Greek Islands
Starting in Southampton, England, UK, Cadiz (tours to Seville), Spain, Mykonos, Greece, Santorini, Greece, Piraeus (tours to Athens), Greece
2026 Sails: Sep 20, More...
Cunard Line, Queen Anne
Queen Anne19 Night - Mediterranean and Greek Islands
Starting in Southampton, England, UK, Cadiz (tours to Seville), Spain, Mykonos, Greece, Santorini, Greece, Piraeus (tours to Athens), Greece, Heraklion, Crete, Greece, Katakolon (tours to Olympia), Greece, Cagliari, Sardinia, Italy, Gibraltar, Southampton, England, UK
2026 Sails: Sep 20, More...
Fred Olsen Cruise Lines, Borealis
Borealis7 Night - Western Europe Roundtrip from Southampton
Starting in Southampton, Santander, Getxo (Bilbao), Gijon, Spain, La Coruna, Southampton
2026 Sails: Sep 21, More...
Royal Caribbean, Liberty of the Seas
Liberty of the Seas8 Night - Spain & France Cruise
Starting in Southampton, England, Paris (Le Havre), France, Bilbao, La Coruna, Spain, Vigo, Spain, Cherbourg, France, Southampton, England
2026 Sails: Sep 25, More...
Celebrity Cruises, Celebrity Apex
Celebrity Apex11 Night - Canaries & Portugal Cruise
Starting in Southampton, England, Porto (Leixoes), Portugal, Madeira (Funchal), Portugal, Tenerife, Canary Islands, Gran Canaria, Canary Islands, Lisbon, Portugal, Vigo, Spain, Southampton, England
2026 Sails: Sep 26, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa3 Night - Northern Europe
Starting in Southampton (London), United Kingdom, Zeebrugge (Bruges), Belgium, Cherbourg (Mont Saint-Michel), France, Southampton (London), United Kingdom
2026 Sails: Sep 26, More...
Princess Cruises, Sky Princess
Sky Princess14 Night - Oktoberfest European Capitals
Starting in Southampton (for London), England, Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Rotterdam, the Netherlands, Skagen, Denmark, Copenhagen, Denmark, Aarhus, Denmark, Kristiansand, Norway, Oslo, Norway, Hamburg, Germany (for Berlin), Southampton (for London), England
2026 Sails: Sep 26, More...
Fred Olsen Cruise Lines, Borealis
Borealis18 Night - Western Mediterranean Roundtrip from Southampton
Starting in Southampton, Gibraltar, Cartagena ES, Cap De Formentor, Pass North Coastline of Menorca, Propriano, Olbia, Pass Amalfi Coast, Salerno, Sorrento, Pass Maratea Coast, Cagliari, Lisbon, Southampton
2026 Sails: Sep 28, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa4 Night - Northern Europe
Starting in Southampton (London), United Kingdom, Cork, Ireland, Southampton (London), United Kingdom
2026 Sails: Sep 29, Oct 15, More...

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Southampton Cruise Departures