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Puerto Rico Cruise Departures

Cruises that depart from Caribbean: Puerto Rico

Cruises that visit Puerto Rico

Click on a cruise ship itinerary sailing from Puerto Rico (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Puerto Rico), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: San Juan

Departing from
Puerto Rico
Cruise Specials

Ritz-Carlton, Ilma
Ilma7 Night - San Juan / Miami, Florida
Starting in San Juan, Jost Van Dyke, St John VI, Grand Turk, Bimini, Miami, Florida
2028 Sails: Mar 9, More...
SeaDream Yacht Club, SeaDream II
SeaDream II7 Night - Cruise Roundtrip from San Juan
Starting in San Juan, Culebra, Esperanza, Vieques Island, St John VI (Cruz Bay), US Virgin Islands, Saba, Gustavia, White Bay, Jost van Dyke, Spanish Town, Virgin Gorda, Leverick Bay, Virgin Gorda, San Juan
2028 Sails: Mar 11, More...
Virgin Voyages, Scarlet Lady
Scarlet Lady7 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, Charlotte Amalie, St Thomas, Bridgetown, Barbados, Fort-De-France, Martinique, Roseau, Dominica, Philipsburg, Sint Maarten, San Juan, Puerto Rico
2028 Sails: Mar 11, More...
EXPLORA II7 Night - A Journey Through Tropical Utopia & Rhythmic Streets
Starting in San Juan, Tortola / Road Town, Gustavia, Frederiksted, Saint Croix, Ocean Cay, Miami
2028 Sails: Mar 12, More...
EXPLORA IV7 Night - A Journey Through Historical Gems & Idyllic Coastlines
Starting in San Juan, St John VI (Cruz Bay), US Virgin Islands, Pointe-a-Pitre, Marigot, Ocean Cay, Miami
2028 Sails: Mar 18, Apr 15, More...
Norwegian Cruise Line, Norwegian Prima
Norwegian Prima7 Night - Southern Caribbean - San Juan
Starting in San Juan, Pr, Tortola, British Virgin Islands, Basseterre, Saint Kitts / Nevis, Philipsburg, St Maarten, Netherland Antilles, Bridgetown, Barbados, St Lucia, Saint Lucia, St Thomas, Vi, San Juan, Pr
2028 Sails: Mar 18, More...
SeaDream Yacht Club, SeaDream II
SeaDream II7 Night - Cruise from San Juan to West Palm Beach
Starting in San Juan, Samana, Grand Turk, Sailing the Bahamas Archipelago, Gordons Beach, Long Island, Staniel Cay, Exumas, Taino Beach, Grand Bahama, Palm Beach
2028 Sails: Mar 25, More...
Virgin Voyages, Scarlet Lady
Scarlet Lady7 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, Philipsburg, Sint Maarten, Bridgetown, Barbados, Fort-De-France, Martinique, Basseterre, Saint Kitts and Nevis, Charlotte Amalie, St Thomas, San Juan, Puerto Rico
2028 Sails: Mar 25, More...
Princess Cruises, Emerald Princess
Emerald Princess7 Night - Southern Caribbean with Abc Islands
Starting in San Juan, Puerto Rico, Curacao, Aruba, Bonaire, Caribbean Netherlands, Fort Lauderdale, Florida
2028 Sails: Mar 26, More...
Windstar, Star Pride
Star Pride23 Night - Star Collector : Tropical Horizons to Historic Amsterdam
Starting in San Juan, St Georges, Bequia, Mayreau, Les Saintes, Marigot, St Martin, San Juan, Lisbon, Brest, Amsterdam
2028 Sails: Mar 27, More...

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Puerto Rico Cruise Departures