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Puerto Rico Cruise Departures

Cruises that depart from Caribbean: Puerto Rico

Cruises that visit Puerto Rico

Click on a cruise ship itinerary sailing from Puerto Rico (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Puerto Rico), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: San Juan

Departing from
Puerto Rico
Cruise Specials

Explora Journeys, EXPLORA I
EXPLORA I9 Night - A Journey from Painted Streets to Sculpted Shores
Starting in San Juan, St Maarten / Philipsburg, Santa Cruz de Tenerife, Arrecife (Lanzarote)
2026 Sails: Mar 12, More...
Explora Journeys, EXPLORA I
EXPLORA I13 Night - A Journey Through Atlantic Breezes and Mediterranean Grace
Starting in San Juan, St Maarten / Philipsburg, Santa Cruz de Tenerife, Arrecife (Lanzarote), Tangier, Barcelona
2026 Sails: Mar 12, More...
Ritz-Carlton, Evrima
Evrima3 Night - San Juan / San Juan
Starting in San Juan, St John VI, Gustavia, San Juan
2026 Sails: Mar 12, More...
Windstar, Star Seeker
Star Seeker7 Night - Windward Islands Surf & Sunsets
Starting in San Juan, Marigot, St Martin, Les Saintes, Mayreau, Bequia, Pigeon Island, The Pitons, San Juan
2026 Sails: Mar 13, More...
Ritz-Carlton, Ilma
Ilma5 Night - San Juan / San Juan
Starting in San Juan, Virgin Gorda, Gustavia, Marigot, St Thomas, San Juan
2026 Sails: Mar 14, More...
Virgin Voyages, Valiant Lady
Valiant Lady7 Night - Southern Caribbean & Aruban Nights
Starting in San Juan, Puerto Rico, Oranjestad, Aruba, Willemstad AN, Curacao, Fort-De-France, Martinique, Basseterre, Saint Kitts and Nevis, San Juan, Puerto Rico
2026 Sails: Mar 14, Dec 5, 2027: Jan 9, Feb 13, Feb 27, Apr 3, More...
Princess Cruises, Grand Princess
Grand Princess14 Night - Southern Caribbean Adventurer
Starting in San Juan, Puerto Rico, Tortola, British Virgin Islands, St Kitts, Dominica, Grenada, Barbados, San Juan, Puerto Rico, St Thomas, US Virgin Islands, St Maarten, Antigua, Dominica, Barbados, San Juan, Puerto Rico
2026 Sails: Mar 15, More...
Ritz-Carlton, Evrima
Evrima5 Night - San Juan / San Juan
Starting in San Juan, St John VI, Gustavia, Marigot, Virgin Gorda, San Juan
2026 Sails: Mar 15, More...
Royal Caribbean, Brilliance of the Seas
Brilliance of the Seas7 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, St Croix, US Virgin Islands, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, San Juan, Puerto Rico
2026 Sails: Mar 15, More...
Ritz-Carlton, Ilma
Ilma7 Night - San Juan / Fort Lauderdale, Florida
Starting in San Juan, Samana, Puerto Plata, Dominican Republic, Grand Turk, Sandy Point (Marina Day), Bimini, Fort Lauderdale, Florida
2026 Sails: Mar 19, More...

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Puerto Rico Cruise Departures