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Puerto Rico Cruise Departures

Cruises that depart from Caribbean: Puerto Rico

Cruises that visit Puerto Rico

Click on a cruise ship itinerary sailing from Puerto Rico (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Puerto Rico), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: San Juan

Departing from
Puerto Rico
Cruise Specials

Royal Caribbean, Vision of the Seas
Vision of the Seas10 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, Charlotte Amalie, St Thomas, St Croix, US Virgin Islands, Philipsburg, St Maarten, St Johns AG, Antigua, Roseau, Dominica, Castries, St Lucia, Basseterre, St Kitts and Nevis, Miami, Florida
2027 Sails: Apr 4, More...
Explora Journeys, EXPLORA III
EXPLORA III7 Night - A Journey Through Balmy Shores & Stirring Scenery
Starting in San Juan, Gustavia, Little Bay, Basseterre, Key West, Miami
2027 Sails: Apr 5, More...
Explora Journeys, EXPLORA III
EXPLORA III17 Night - A Grand Journey Through Balmy Shores & Enchanting Nature to Panama's Wonders
Starting in San Juan, Gustavia, Little Bay, Basseterre, Key West, Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 5, More...
Virgin Voyages, Valiant Lady
Valiant Lady5 Night - Eastern Caribbean : San Juan to Miami
Starting in San Juan, Puerto Rico, Grand Turk, Turks and Caicos, The Beach Club at Bimini, Bahamas, Miami, Florida
2027 Sails: Apr 10, More...
Disney Cruise Line, Disney Dream
Disney Dream7 Night - Southern Caribbean Cruise from San Juan
Starting in San Juan, Curacao, Aruba, Antigua, Philipsburg, St Maarten, San Juan
2027 Sails: Apr 16, More...
SeaDream Yacht Club, SeaDream I
SeaDream I14 Night - Cruise from San Juan to Lisbon
Starting in San Juan, White Bay, Jost van Dyke, Funchal, Madeira, Lisbon
2027 Sails: Apr 17, More...
Disney Cruise Line, Disney Dream
Disney Dream4 Night - Eastern Caribbean Cruise from San Juan to Port Canaveral
Starting in San Juan, Disney Lookout Cay, Castaway Cay, Port Canaveral
2027 Sails: Apr 23, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, Charlotte Amalie, St Thomas, St Croix, US Virgin Islands, Philipsburg, St Maarten, Castries, St Lucia, Bridgetown, Barbados, San Juan, Puerto Rico
2027 Sails: May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, Nov 13, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in San Juan, Puerto Rico, Tortola, Philipsburg, St Maarten, St Johns AG, Antigua, Basseterre, St Kitts and Nevis, St Croix, US Virgin Islands, San Juan, Puerto Rico
2027 Sails: May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, Nov 6, Nov 20, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity14 Night - South America
Starting in San Juan, St Kitts (Basseterre), Castries, St Lucia, Scarborough, Iles du Salut (Devils Island), Fortaleza, Maceio, Salvador De Bahia, Rio De Janeiro
2027 Sails: Oct 21, More...

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Puerto Rico Cruise Departures