Portugal Cruise Departures

Cruises that depart from Europe: Portugal

Cruises that visit Portugal

See all River Cruises that depart from Portugal

Click on a cruise ship itinerary sailing from Portugal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portugal), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Funchal : Lisbon : Ponta Delgada : Porto

Emerald Cruises, Emerald Sakara

10 Night - Pearls of Southern Spain & Portugal
Starting in Lisbon, Portugal, Portimao, Portugal, Seville, Spain, Tangier, Morocco, Malaga, Spain, Cartagena ES, Ibiza, Spain, Palma De Mallorca, Spain, Mahon, Menorca, Spain, Barcelona, Spain
2026 Sails: Oct 8, More...

Regent Seven Seas, Seven Seas Grandeur

11 Night - Stars of Iberia
Starting in Lisbon, Portimao, Cadiz, Malaga, Almeria, Cruising the Mediterranean Sea, Cagliari (Sardinia), La Goulette, Trapani (Sicily), Cruising the Mediterranean Sea, Valletta
2026 Sails: Oct 9, More...

Viking Ocean, Viking Saturn

7 Night - Spain & Portugal Discovery
Starting in Lisbon, Seville (Cadiz), Tangier, Granada (Malaga), Murcia (Cartagena ES, Spain), Barcelona, Barcelona (Tarragona)
2026 Sails: Oct 10, More...

Crystal Cruises, Crystal Serenity

6 Night - Europe & Mediterranean
Starting in Lisbon, Portimao, Casablanca, Morocco, Agadir, Arrecife, Canary Islands, Lisbon
2026 Sails: Oct 11, More...

PONANT, Le Laperouse

13 Night - Lisbon to the Canary Islands by Sea : Spain, Morocco, & Atlantic Isles - with Smithsonian Journeys
Starting in Lisbon, Portimao, Cadiz, Marbella, Malaga, Tangier, Casablanca, Funchal, Madeira, Santa Cruz de La Palma, Santa Cruz de Tenerife, Las Palmas de Gran Canaria, Canary Islands
2026 Sails: Oct 12, More...

Star Clippers, Royal Clipper

15 Night - Westbound Atlantic Ocean Crossing
Starting in Lisbon, Portugal, Portimao, Portugal, Funchal / Madeira, Portugal, Bridgetown, Barbados
2026 Sails: Oct 16, More...

AmaWaterways Tours, AmaDouro Tours

10 Night - Enticing Douro with Lisbon Pre-Cruise
Starting in Lisbon, Porto, El Dorado, Pinhao, Vega de Terron, Bermuda, Pinhao, Porto
2026 Sails: Oct 17, Oct 24, Nov 14, More...

Norwegian Cruise Line, Norwegian Dawn

7 Night - Europe
Starting in Lisbon, Portugal, Cadiz / Seville, Spain, Motril, Spain, Gibraltar, Ibiza, Spain, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Oct 18, More...

AmaWaterways, AmaDouro

7 Night - Enticing Douro
Starting in Porto, El Dorado, Pinhao, Vega de Terron, Bermuda, Pinhao, Porto
2026 Sails: Oct 20, Oct 27, Nov 17, Dec 1, Dec 8, Dec 15, Dec 29, More...

AmaWaterways Tours, AmaSintra Tours

10 Night - Enticing Douro with Lisbon Pre-Cruise
Starting in Lisbon, Porto, El Dorado, Pinhao, Vega de Terron, Bermuda, Pinhao, Porto
2026 Sails: Oct 20, Oct 27, More...

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Portugal Cruise Departures