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Luxembourg Cruise Departures

Cruises that depart from Europe: Luxembourg

Cruises that visit Luxembourg

See all River Cruises that depart from Luxembourg

Click on a cruise ship itinerary sailing from Luxembourg (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Luxembourg), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Remich


AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Rhine & Moselle Splendors (Wine Cruise)
Starting in Luxembourg, Wasserbillig, Cochem, Moselle Valley, Koblenz, Rhine Gorge, Rudesheim, Ludwigshafen, Strasbourg, Breisach, Basel
2026 Sails: Apr 22, Oct 7, 2027: Aug 18, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises7 Night - The Rhine & Moselle : Canals, Vineyards and Castles
Starting in Remich, Luxembourg (Embarkation), Remich Excursion to Luxembourg, Bernkastel, Germany, Cochem, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 10, Jul 1, Aug 3, Sep 5, More...
AmaWaterways, AmaCerto
AmaCerto Cruises7 Night - Europe's Rivers & Castles
Starting in Luxembourg, Bernkastel, Cochem, Koblenz, Rhine Gorge, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg
2026 Sails: Jul 1, Aug 26, Oct 21, More...
AmaWaterways, AmaCerto
AmaCerto Cruises7 Night - Rhine & Moselle Splendors (Wine Cruise)
Starting in Luxembourg, Wasserbillig, Cochem, Moselle Valley, Koblenz, Rhine Gorge, Rudesheim, Ludwigshafen, Strasbourg, Breisach, Basel
2026 Sails: Jul 15, Nov 4, 2027: Apr 7, Jul 28, More...
AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Europe's Rivers & Castles
Starting in Luxembourg, Bernkastel, Cochem, Koblenz, Rhine Gorge, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg
2026 Sails: Jul 29, More...
AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Rhine & Moselle Splendors
Starting in Luxembourg, Wasserbillig, Cochem, Moselle Valley, Koblenz, Rhine Gorge, Rudesheim, Ludwigshafen, Strasbourg, Breisach, Basel
2026 Sails: Aug 12, 2027: May 12, Jul 7, Sep 29, More...
AmaWaterways, AmaCerto
AmaCerto Cruises7 Night - Rhine & Moselle Splendors
Starting in Luxembourg, Wasserbillig, Cochem, Moselle Valley, Koblenz, Rhine Gorge, Rudesheim, Ludwigshafen, Strasbourg, Breisach, Basel
2026 Sails: Sep 9, 2027: May 19, Sep 8, Oct 20, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises7 Night - The Rhine & Moselle : Canals, Vineyards and Castles
Starting in Remich, Luxembourg (Embarkation), Remich / Trier, Bernkastel, Germany, Cochem, Koblenz / Cologne, Dusseldorf, Nijmegen, Holland, Amsterdam (Disembarkation)
2027 Sails: Jul 1, Aug 23, Sep 25, More...

Luxembourg Cruise Departures