Lisbon Cruise Departures
Cruises that depart from Europe: Portugal: Lisbon
Cruises that visit Lisbon
See all River Cruises that depart from Lisbon
12 Night - Spanish Symphony & Madrid Medley Cruise Tour
Starting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Madrid, Spain
2026 Sails: Jun 22, More...15 Night - Star Collector : Enchantment of the Western Med
Starting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Palamos, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Rome
2026 Sails: Jun 22, More...8 Night - Spanish Symphony
Starting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona
2026 Sails: Jun 22, More...
20 Night - Wine Country to Fjords
Starting in Lisbon, Oporto, La Coruna, Bilbao, Bordeaux (Le Verdon), Pont-Aven (Concarneau), Saint-malo, London (Southampton), Paris (Le Havre), Bruges (Zeebrugge), Ijmuiden, Edinburgh (Leith), Aberdeen, Invergordon, United Kingdom, Lerwick (Shetland Islands), Maloy, Alesund, Stavanger, Arendal, Oslo
2026 Sails: Jun 23, More...7 Night - Vineyards & Vistas
Starting in Lisbon, Oporto, La Coruna, Bilbao, Bordeaux (Le Verdon), Pont-Aven (Concarneau), Saint-malo, London (Southampton)
2026 Sails: Jun 23, More...
10 Night - Delightful Douro with Lisbon
Starting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Barca DAlva, Barca dAlva / Pocinho, Pocinho / Regua, Regua / Porto, Porto
2026 Sails: Jun 23, Jul 27, Sep 22, Nov 5, 2027: Mar 17, Apr 3, Jun 6, Jun 23, Jun 30, Aug 26, Sep 22, Oct 19, Oct 26, Nov 2, Nov 19, More...13 Night - Delightful Douro with Lisbon & Madrid
Starting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Barca DAlva, Barca dAlva / Pocinho, Pocinho / Regua, Regua / Porto, Porto, Porto / Madrid, Madrid
2026 Sails: Jun 23, Jul 27, 2027: Mar 17, Apr 3, Jun 6, Jun 23, Jun 30, Aug 26, Oct 26, Nov 19, More...
13 Night - Lisbon to Madrid with Secrets of the Douro
Starting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto, Porto / Madrid, Madrid
2026 Sails: Jun 24, 2027: Jul 21, Sep 1, Oct 13, Nov 10, More...
23 Night - Mediterranean Constellation
Starting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jun 24, More...11 Night - Legendary Mediterranean
Starting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus)
2026 Sails: Jun 24, More...
Cruises that depart from Europe: Portugal: Lisbon
Cruises that visit Lisbon
See all River Cruises that depart from Lisbon
Click on a cruise ship itinerary sailing from Lisbon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Lisbon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
12 Night - Spanish Symphony & Madrid Medley Cruise TourStarting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Madrid, Spain
2026 Sails: Jun 22, More...
15 Night - Star Collector : Enchantment of the Western MedStarting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona, Palamos, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Rome
2026 Sails: Jun 22, More...
8 Night - Spanish SymphonyStarting in Lisbon, Cadiz, Gibraltar, Malaga, Almeria, Spain, Cartagena ES, Palma De Mallorca, Barcelona
2026 Sails: Jun 22, More...
Deal link -> Special
20 Night - Wine Country to FjordsStarting in Lisbon, Oporto, La Coruna, Bilbao, Bordeaux (Le Verdon), Pont-Aven (Concarneau), Saint-malo, London (Southampton), Paris (Le Havre), Bruges (Zeebrugge), Ijmuiden, Edinburgh (Leith), Aberdeen, Invergordon, United Kingdom, Lerwick (Shetland Islands), Maloy, Alesund, Stavanger, Arendal, Oslo
2026 Sails: Jun 23, More...
Deal link -> Special
7 Night - Vineyards & VistasStarting in Lisbon, Oporto, La Coruna, Bilbao, Bordeaux (Le Verdon), Pont-Aven (Concarneau), Saint-malo, London (Southampton)
2026 Sails: Jun 23, More...
Deal link -> Special
10 Night - Delightful Douro with LisbonStarting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Barca DAlva, Barca dAlva / Pocinho, Pocinho / Regua, Regua / Porto, Porto
2026 Sails: Jun 23, Jul 27, Sep 22, Nov 5, 2027: Mar 17, Apr 3, Jun 6, Jun 23, Jun 30, Aug 26, Sep 22, Oct 19, Oct 26, Nov 2, Nov 19, More...
Deal link -> Special
13 Night - Delightful Douro with Lisbon & MadridStarting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Barca DAlva, Barca dAlva / Pocinho, Pocinho / Regua, Regua / Porto, Porto, Porto / Madrid, Madrid
2026 Sails: Jun 23, Jul 27, 2027: Mar 17, Apr 3, Jun 6, Jun 23, Jun 30, Aug 26, Oct 26, Nov 19, More...
13 Night - Lisbon to Madrid with Secrets of the DouroStarting in Lisbon, Lisbon / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto, Porto / Madrid, Madrid
2026 Sails: Jun 24, 2027: Jul 21, Sep 1, Oct 13, Nov 10, More...
Deal link -> Special
23 Night - Mediterranean ConstellationStarting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jun 24, More...
Deal link -> Special
11 Night - Legendary MediterraneanStarting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus)
2026 Sails: Jun 24, More...
