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Istanbul Cruise Departures

Cruises that depart from Mediterranean: Turkey: Istanbul

Cruises that visit Istanbul

See all River Cruises that depart from Istanbul

Click on a cruise ship itinerary sailing from Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Viking Ocean, Viking Saturn
Viking Saturn7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Nov 21, More...
Viking Ocean, Viking Saturn
Viking Saturn21 Night - Iconic Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Nov 21, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager10 Night - Turkish Treasures
Starting in Istanbul, Cruising the Aegean Sea, Izmir, Cruising the Aegean Sea, Marmaris, Limassol, Rhodes, Heraklion (Crete), Mykonos, Athens (Piraeus)
2026 Sails: Nov 27, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Dec 9, More...
Viking Ocean, Viking Vesta
Viking Vesta14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Dec 9, 2027: Jan 20, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Dec 9, 2027: Jan 20, More...
Viking Ocean, Viking Neptune
Viking Neptune14 Night - Ancient Mediterranean Antiquities
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus), Ephesus (Kusadasi), Crete (Souda Bay), Sail the Ionian Sea, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Dec 22, More...
Viking Ocean, Viking Neptune
Viking Neptune7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Dec 22, More...
MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2026 Sails: Dec 30, More...
MSC Cruises, MSC Orchestra
MSC Orchestra3 Night - Mediterranean
Starting in Istanbul, Turkey, Corfu, Greece, Bari, Italy
2027 Sails: Jan 6, Apr 21, 2028: May 3, More...

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Istanbul Cruise Departures