Ho Chi Minh City Cruise Departures
Cruises that depart from Asia/Far East: Vietnam: Ho Chi Minh City
Cruises that visit Ho Chi Minh City
See all River Cruises that depart from Ho Chi Minh City
12 Night - Wonders of Vietnam, Cambodia & the Mekong
Starting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jan 1, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, More...
14 Night - Magnificent Mekong
Starting in Ho Chi Minh City, Sa Dec, Tan Chau, Phnom Penh, Scenic Sailing : Mekong River, Kampong Cham, Siem Reap, Hanoi
2026 Sails: Jan 5, Jan 19, Feb 16, Mar 16, Mar 30, Aug 10, Aug 24, Sep 7, Sep 21, Oct 5, Oct 19, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Aug 16, Aug 30, More...15 Night - Wonders of Indochina and the Mekong
Starting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation / Siem Reap, Siem Reap, Siem Reap / Luang Prabang, Luang Prabang
2026 Sails: Jan 15, More...7 Night - Majestic Mekong Cruise
Starting in Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation to Phnom Penh
2026 Sails: Jan 17, Feb 14, Feb 28, Mar 14, Mar 28, May 9, More...
11 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap Post-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...9 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...15 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap, Hanoi, Ha Long Bay, Hanoi Post-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap, Hanoi, Ha Long Bay, Hanoi
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Mar 6, Mar 20, Apr 3, Apr 17, More...7 Night - Charms of the Mekong
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 9, Mar 9, Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 5, Oct 19, Nov 2, Nov 30, Dec 14, Dec 28, 2027: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Sep 6, More...9 Night - Charms of the Mekong with Siem Reap Post-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 9, Mar 9, Apr 6, Apr 20, 2027: Jan 11, Jan 25, Feb 8, Mar 8, Mar 22, Apr 5, Apr 19, More...
14 Night - Magnificent Mekong
Starting in Ho Chi Minh City, Sa Dec, Tan Chau, Phnom Penh, Scenic Sailing : Mekong River, Kampong Cham, Siem Reap, Hanoi
2026 Sails: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Aug 17, Aug 31, Sep 14, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Aug 9, Aug 23, Sep 6, More...
Cruises that depart from Asia/Far East: Vietnam: Ho Chi Minh City
Cruises that visit Ho Chi Minh City
See all River Cruises that depart from Ho Chi Minh City
Click on a cruise ship itinerary sailing from Ho Chi Minh City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Ho Chi Minh City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
12 Night - Wonders of Vietnam, Cambodia & the MekongStarting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jan 1, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, More...
14 Night - Magnificent MekongStarting in Ho Chi Minh City, Sa Dec, Tan Chau, Phnom Penh, Scenic Sailing : Mekong River, Kampong Cham, Siem Reap, Hanoi
2026 Sails: Jan 5, Jan 19, Feb 16, Mar 16, Mar 30, Aug 10, Aug 24, Sep 7, Sep 21, Oct 5, Oct 19, Nov 16, Nov 30, Dec 14, Dec 28, 2027: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Aug 16, Aug 30, More...
15 Night - Wonders of Indochina and the MekongStarting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation / Siem Reap, Siem Reap, Siem Reap / Luang Prabang, Luang Prabang
2026 Sails: Jan 15, More...
7 Night - Majestic Mekong CruiseStarting in Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation to Phnom Penh
2026 Sails: Jan 17, Feb 14, Feb 28, Mar 14, Mar 28, May 9, More...
11 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap Post-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...
9 Night - Charms of the Mekong with Ho Chi Minh City Pre-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...
15 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap, Hanoi, Ha Long Bay, Hanoi Post-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap, Hanoi, Ha Long Bay, Hanoi
2026 Sails: Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Mar 6, Mar 20, Apr 3, Apr 17, More...
7 Night - Charms of the MekongStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 9, Mar 9, Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 5, Oct 19, Nov 2, Nov 30, Dec 14, Dec 28, 2027: Jan 11, Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, Aug 9, Sep 6, More...
9 Night - Charms of the Mekong with Siem Reap Post-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Feb 9, Mar 9, Apr 6, Apr 20, 2027: Jan 11, Jan 25, Feb 8, Mar 8, Mar 22, Apr 5, Apr 19, More...
14 Night - Magnificent MekongStarting in Ho Chi Minh City, Sa Dec, Tan Chau, Phnom Penh, Scenic Sailing : Mekong River, Kampong Cham, Siem Reap, Hanoi
2026 Sails: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Aug 17, Aug 31, Sep 14, Oct 12, Oct 26, Nov 9, Nov 23, Dec 7, Dec 21, 2027: Jan 4, Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Aug 9, Aug 23, Sep 6, More...
