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Brussels Cruise Departures

Cruises that depart from Europe: Belgium: Brussels

Cruises that visit Brussels

See all River Cruises that depart from Brussels

Click on a cruise ship itinerary sailing from Brussels (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Brussels), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Uniworld Boutique River Cruise Collection, S.S. Victoria
S.S. Victoria Cruises14 Night - Rhine, Moselle & Belgium Grand Discovery
Starting in Brussels, Antwerp, Maastricht, Roermond, Dusseldorf, Cologne, Cochem, Trier, Bernkastel, Koblenz, Boppard, Boppard, Rudesheim, Speyer, Strasbourg (Baden-Baden), Basel (Lucerne), Basel
2026 Sails: Jul 18, Aug 15, 2027: Jun 20, Jul 18, Aug 15, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises20 Night - Belgian Delights & Splendours of Europe & Prague
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Aug 5, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Aug 5, Oct 14, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises17 Night - Romantic Rhine & Moselle with Bruges
Starting in Brussels / Bruges, Bruges, Bruges / Amsterdam, Dordrecht, Bruinisse, Antwerp, Arnhem, Dusseldorf, Cochem, Bernkastel, Koblenz, Rudesheim, Mannheim, Strasbourg, Breisach, Basel / Zurich
2026 Sails: Sep 13, 2027: Sep 19, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises17 Night - Romantic Rhine & Moselle with Bruges
Starting in Brussels / Bruges, Bruges, Bruges / Amsterdam, Dordrecht, Bruinisse, Antwerp, Arnhem, Dusseldorf, Cochem, Bernkastel, Koblenz, Rudesheim, Mannheim, Strasbourg, Breisach, Basel
2026 Sails: Sep 13, 2027: Sep 19, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Sep 25, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 28, 2027: Sep 1, More...
Uniworld Boutique River Cruise Collection, S.S. Victoria
S.S. Victoria Cruises10 Night - Dutch & Belgian Holiday Celebration
Starting in Brussels, Ghent, Hasselt, Maastricht, Antwerp, Rotterdam, Rotterdam, Amsterdam, Amsterdam
2026 Sails: Dec 23, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises13 Night - Belgian & Holland Delights with Copenhagen
Starting in Brussels, Brussels / Amsterdam, Amsterdam / Zaanse Schans, Rotterdam (the Hague) Willemstad NL, Rotterdam, Antwerp, Nijmegen, Amsterdam, Amsterdam / Copenhagen, Copenhagen
2027 Sails: Apr 2, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises10 Night - Belgian Delights & Holland in Bloom
Starting in Brussels, Brussels / Amsterdam, Amsterdam / Zaanse Schans, Rotterdam (the Hague) Willemstad NL, Rotterdam, Antwerp, Nijmegen, Amsterdam
2027 Sails: Apr 2, More...

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Brussels Cruise Departures