South America Cruise Specials
We've gathered all of the South America cruise specials ordered by sail date. Click on a special and select a sail date to get a single cruise quote from the cruise agency that posted that particular special. To search through all cruise itineraries (not just South America cruises) to receive multiple custom cruise options to compare, please visit our Cruise Search page.
Crystal Cruises, Crystal Serenity
10 Nights Caribbean & Panama Canal Cruise from $5000 pp10 Night - The Americas & Caribbean - Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City), Puntarenas
2026 Sails: Dec 2 Get a Quote
Crystal Cruises, Crystal Serenity
8 Nights Caribbean and Central America Cruise from $4700 pp8 Night - The Americas & Caribbean - Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City)
2026 Sails: Dec 2 Get a Quote
Crystal Cruises, Crystal Serenity
10 Nights Caribbean & Panama Canal Cruise from $5500 pp10 Night - The Americas & Caribbean - Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City), Puntarenas
2026 Sails: Dec 2 Get a Quote
Celebrity Cruises, Celebrity Equinox
Up to $200 Extra OBC and Specialty Dining for 2 $100114 Night - Patagonia & Argentina Cruise - Starting in Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Cape Horn, Chile, Ushuaia, Argentina, Strait of Magellan, Punta Arenas, Chile, Puerto Madryn, Argentina, Punta Del Este, Uruguay, Buenos Aires, Argentina
2026 Sails: Dec 5, Dec 19 Get a Quote
Oceania Cruises, Oceania Insignia
15 Nights Antilles To Andes Voyage from $4399 pp15 Night - Antilles to Andes - Starting in Miami, Key West, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Panama Canal Daylight Transit, Manta, Guayaquil, Lima / Machu Picchu (Callao)
2026 Sails: Dec 19 Get a Quote
Holland America, Nieuw Amsterdam
21 Nights Panama Canal & Southern Caribbean Holiday Cruise from $2049 pp21 Night - Panama Canal & Southern Caribbean Holiday - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27 Get a Quote
Holland America, Nieuw Amsterdam
21 Nights Panama Canal & Southern Caribbean Holiday Cruise from $2049 pp21 Night - Panama Canal & Southern Caribbean Holiday - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27 Get a Quote
Celebrity Cruises, Celebrity Equinox
14 Nights Antarctica Cruise from $3698 pp plus OBC14 Night - Antarctica Cruise - Starting in Buenos Aires, Argentina, Ushuaia, Argentina, Cape Horn, Chile, Schollaert Channel, Antarctica, Paradise Bay, Antarctica, Gerlache Strait, Elephant Island, Antarctica, Port Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina
2027 Sails: Jan 2 Get a Quote
MSC Cruises, MSC Musica
7 Nights South America Cruise from $946 pp plus OBC7 Night - South America - Starting in Paranagua, Brazil, Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Buzios, Brazil, Ilha Grande, Brazil, Paranagua, Brazil
2027 Sails: Jan 2 Get a Quote
Holland America, Volendam
35 Night Grand World Voyage from $6096 pp35 Night - Grand World Voyage - Starting in Fort Lauderdale, Florida, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Crossing the Equator, Manta, Ecuador, Callao (Lima), Peru, Easter Island, Chile, Scenic Cruising Pitcairn Island, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Bora Bora, French Polynesia, Cross International Dateline, Apia, Upolu, Samoa, Savusavu, Vanua Levu, Fiji, Suva, Viti Levu, Fiji, Easo, Lifou, New Caledonia, Noumea, New Caledonia
2027 Sails: Jan 5 Get a Quote
South America Cruise Specials
