Mekong River Cruises
River Cruises sailing on the Mekong River
River cruises by river name
Cruises on the Mekong River also sail: Chao Phraya River : Japan Coast : Laos Waterways : Perfume River : Ping River : Red River : Saigon River : Thailand Waterways : Thu Bon River : Tonle Sap Lake : Tonle Sap River : Vietnam Waterways
7 Night - Majestic Mekong Cruise
Starting in Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation to Phnom Penh
2026 Sails: Jan 17, Feb 14, Feb 28, Mar 14, Mar 28, May 9, More...
7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 23, Mar 6, Mar 20, Oct 30, Nov 13, Dec 25, 2028: Jan 8, Jan 22, Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, More...3 Night - Phnom Penh and Siem Reap
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, More...
4 Night - Phnom Penh and Siem Reap
Starting in Phnom Penh, Tonle Sap River, Oudong Meditations and Pak Russei Silk, Peam Chi Korng Pottery Village, Siem Reap Disembarkation
2026 Sails: Jan 20, Feb 3, Mar 3, Mar 17, More...4 Night - Saigon and Phnom Penh Short Cruise
Starting in Phnom Penh Embarkation, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 21, Feb 4, Feb 18, Mar 4, Mar 18, Apr 1, Nov 3, More...
11 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap Post-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...9 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...15 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap, Hanoi, Ha Long Bay, Hanoi Post-Cruise
Starting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap, Hanoi, Ha Long Bay, Hanoi
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Mar 6, Mar 20, Apr 3, Apr 17, More...7 Night - Classic Mekong
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 24, Mar 7, Mar 21, Oct 24, Nov 21, Dec 5, Dec 19, 2027: Jan 2, Feb 13, Mar 13, Oct 9, Oct 23, Nov 6, Nov 20, 2028: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, More...3 Night - Phnom Penh and Siem Reap
Starting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Jan 24, Mar 7, Mar 21, More...
River Cruises sailing on the Mekong River
Click on a cruise ship itinerary sailing on the Mekong River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mekong River), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the Mekong River also sail: Chao Phraya River : Japan Coast : Laos Waterways : Perfume River : Ping River : Red River : Saigon River : Thailand Waterways : Thu Bon River : Tonle Sap Lake : Tonle Sap River : Vietnam Waterways
7 Night - Majestic Mekong CruiseStarting in Ho Chi Minh City / Mekong Cruise, Ben Tre, Sa Dec / My An Hung, Gieng Island / An Long, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Oudong / Prek KDam, Prek KDam Disembarkation to Phnom Penh
2026 Sails: Jan 17, Feb 14, Feb 28, Mar 14, Mar 28, May 9, More...
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 23, Mar 6, Mar 20, Oct 30, Nov 13, Dec 25, 2028: Jan 8, Jan 22, Feb 5, Feb 19, Mar 4, Mar 18, Apr 1, More...
3 Night - Phnom Penh and Siem ReapStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, More...
4 Night - Phnom Penh and Siem ReapStarting in Phnom Penh, Tonle Sap River, Oudong Meditations and Pak Russei Silk, Peam Chi Korng Pottery Village, Siem Reap Disembarkation
2026 Sails: Jan 20, Feb 3, Mar 3, Mar 17, More...
4 Night - Saigon and Phnom Penh Short CruiseStarting in Phnom Penh Embarkation, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 21, Feb 4, Feb 18, Mar 4, Mar 18, Apr 1, Nov 3, More...
11 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap Post-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...
9 Night - Charms of the Mekong with Ho Chi Minh City Pre-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, More...
15 Night - Charms of the Mekong with Ho Chi Minh City Pre-Cruise and Siem Reap, Hanoi, Ha Long Bay, Hanoi Post-CruiseStarting in Ho Chi Minh City, My Tho, Cai Be, Sa Dec, Tan Chau, Border Crossing, Phnom Penh, Oudong, Phnom Penh, Oknhatey Village, Angkor Ban, Kampong Cham, Siem Reap, Hanoi, Ha Long Bay, Hanoi
2026 Sails: Jan 24, Feb 7, Mar 7, Apr 4, Apr 18, 2027: Jan 9, Jan 23, Feb 6, Mar 6, Mar 20, Apr 3, Apr 17, More...
7 Night - Classic MekongStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh, Into, Vietnam, Chau Doc and the Fertile Waterways, Ben Tre and Sailing Into Saigon, Saigon Disembarkation
2026 Sails: Jan 24, Mar 7, Mar 21, Oct 24, Nov 21, Dec 5, Dec 19, 2027: Jan 2, Feb 13, Mar 13, Oct 9, Oct 23, Nov 6, Nov 20, 2028: Jan 1, Jan 15, Jan 29, Feb 12, Feb 26, Mar 11, Mar 25, Apr 8, Apr 22, More...
3 Night - Phnom Penh and Siem ReapStarting in Siem Reap to the Mekong, Peam Chi Korng and Pak Russei Crafts, Tonle Sap River, Phnom Penh Disembarkation
2026 Sails: Jan 24, Mar 7, Mar 21, More...
