Mekong River Cruises
River Cruises sailing on the Mekong River
River cruises by river name
Cruises on the Mekong River also sail:
Cambodia Waterways : Chao Phraya River : Japan Coast : Laos Waterways : Perfume River : Ping River : Red River : Saigon River : Thailand Waterways : Thu Bon River : Tonle Sap Lake : Tonle Sap River : Vietnam Waterways
7 Night - Majestic Mekong Cruise
Starting in Phnom Penh / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation
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12 Night - Treasures of the Mekong
Starting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: May 17, Sep 27, Oct 25, Nov 8, 2027: Feb 21, Mar 21, Apr 4, Apr 18, May 2, May 16, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 26, More...15 Night - Journey Along the Mekong
Starting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Siem Reap / Vientiane, Vientiane / Luang Prabang, Luang Prabang, Luang Prabang / Bangkok
2026 Sails: May 17, More...10 Night - Luxury Mekong and Temple Discovery Cruise
Starting in Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: May 19, Sep 29, Oct 27, Nov 10, 2027: Jan 12, Feb 23, Mar 23, Apr 6, Apr 20, May 4, May 18, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 28, More...14 Night - Treasures of the Mekong Meandering Cruise
Starting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be, Sa Dec, Tan Chau, Border Crossing / Phnom Penh, Phnom Penh, Phnom Penh / Oudong / Silk Island, Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jul 19, Aug 6, Aug 24, Sep 11, Dec 6, Dec 24, 2027: Jul 18, Aug 5, Aug 23, Sep 10, Dec 7, More...12 Night - Meandering Along the Mekong and Temple Discovery Cruise
Starting in Ho Chi Minh City / Mekong Cruise, Cai Be, Sa Dec, Tan Chau, Border Crossing / Phnom Penh, Phnom Penh, Phnom Penh / Oudong / Silk Island, Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jul 21, Aug 8, Aug 26, Sep 13, Dec 8, Dec 26, 2027: Jul 20, Aug 7, Aug 25, Sep 12, Dec 9, More...14 Night - Treasures of the Mekong Meandering Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...12 Night - Temple Discovery and Meandering Along the Mekong Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...14 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Jul 31, Aug 18, Sep 5, Dec 16, 2027: Jan 3, Jul 30, Aug 17, Sep 4, Dec 17, More...22 Night - Grand Tour of Vietnam & Cambodia
Starting in Hanoi, Hanoi / Halong Bay, Halong Bay, Halong Bay / Hanoi, Hanoi / Danang / Hoi An, Hoi An, Hoi An / Hue, Hue / Ho Chi Minh City, Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cho Gao Canal / Ben Tre, Sa Dec, My An Hung, Gieng Island, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Angkor Ban, Angkor Ban / Peam Chi Korng, Peam Chi Korng Disembarkation / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Aug 2, Aug 20, 2027: Aug 1, Aug 19, Dec 1, More...
River Cruises sailing on the Mekong River
Click on a cruise ship itinerary sailing on the Mekong River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mekong River), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the Mekong River also sail:
Cambodia Waterways : Chao Phraya River : Japan Coast : Laos Waterways : Perfume River : Ping River : Red River : Saigon River : Thailand Waterways : Thu Bon River : Tonle Sap Lake : Tonle Sap River : Vietnam Waterways
7 Night - Majestic Mekong CruiseStarting in Phnom Penh / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation
More...
12 Night - Treasures of the MekongStarting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: May 17, Sep 27, Oct 25, Nov 8, 2027: Feb 21, Mar 21, Apr 4, Apr 18, May 2, May 16, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 26, More...
15 Night - Journey Along the MekongStarting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Siem Reap / Vientiane, Vientiane / Luang Prabang, Luang Prabang, Luang Prabang / Bangkok
2026 Sails: May 17, More...
10 Night - Luxury Mekong and Temple Discovery CruiseStarting in Ho Chi Minh City / Mekong Cruise, Cai Be / Sa Dec, Tan Chau / Border Crossing, Phnom Penh, Phnom Penh / Oudong, Silk Island / Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: May 19, Sep 29, Oct 27, Nov 10, 2027: Jan 12, Feb 23, Mar 23, Apr 6, Apr 20, May 4, May 18, Sep 28, Oct 12, Oct 26, Nov 9, Nov 23, Dec 28, More...
14 Night - Treasures of the Mekong Meandering CruiseStarting in Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cai Be, Sa Dec, Tan Chau, Border Crossing / Phnom Penh, Phnom Penh, Phnom Penh / Oudong / Silk Island, Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jul 19, Aug 6, Aug 24, Sep 11, Dec 6, Dec 24, 2027: Jul 18, Aug 5, Aug 23, Sep 10, Dec 7, More...
12 Night - Meandering Along the Mekong and Temple Discovery CruiseStarting in Ho Chi Minh City / Mekong Cruise, Cai Be, Sa Dec, Tan Chau, Border Crossing / Phnom Penh, Phnom Penh, Phnom Penh / Oudong / Silk Island, Angkor Ban, Wat Hanchey / Kampong Cham, Mekong Cruise / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Jul 21, Aug 8, Aug 26, Sep 13, Dec 8, Dec 26, 2027: Jul 20, Aug 7, Aug 25, Sep 12, Dec 9, More...
14 Night - Treasures of the Mekong Meandering CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
12 Night - Temple Discovery and Meandering Along the Mekong CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Kampong Cham / Angkor Ban, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec, Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: Jul 27, Aug 14, Sep 1, Dec 14, 2027: Jul 26, Aug 13, Aug 31, Nov 27, Dec 15, More...
14 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Jul 31, Aug 18, Sep 5, Dec 16, 2027: Jan 3, Jul 30, Aug 17, Sep 4, Dec 17, More...
22 Night - Grand Tour of Vietnam & CambodiaStarting in Hanoi, Hanoi / Halong Bay, Halong Bay, Halong Bay / Hanoi, Hanoi / Danang / Hoi An, Hoi An, Hoi An / Hue, Hue / Ho Chi Minh City, Ho Chi Minh City, Ho Chi Minh City / Mekong Cruise, Cho Gao Canal / Ben Tre, Sa Dec, My An Hung, Gieng Island, Tan Chau / Vietnam / Cambodia Border Crossing, Phnom Penh, Phnom Penh / Angkor Ban, Angkor Ban / Peam Chi Korng, Peam Chi Korng Disembarkation / Siem Reap, Siem Reap, Depart Siem Reap
2026 Sails: Aug 2, Aug 20, 2027: Aug 1, Aug 19, Dec 1, More...
