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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Avalon Waterways Cruise Tours, Avalon Panorama Cruise Tours
Avalon Panorama Cruise Ship17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Apr 29, May 27, Jun 10, Jun 24, Jul 8, Jul 22, Aug 5, Aug 19, Sep 2, More...
Riviera River Cruises, MS Geoffrey Chaucer
MS Geoffrey Chaucer Cruises14 Night - Cruise the Heart of Europe
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2026 Sails: Apr 29, Sep 30, More...
Viking River, Viking Egdir
Viking Egdir Cruises14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Apr 29, May 27, Jun 24, Jul 22, Aug 19, Sep 16, Oct 14, 2027: May 24, Jun 21, Jul 19, Aug 16, Sep 13, Oct 11, 2028: May 22, Jun 19, Jul 17, Aug 14, Sep 11, Oct 9, More...
AmaWaterways Cruise Tours, AmaLea Cruise Tours
AmaLea Cruise Tours16 Night - Magnificent Europe with Budapest Pre-Cruise
Starting in Budapest, Bratislava, Vienna, Durnstein, Melk, Linz, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Freudenberg, Rudesheim, Lahnstein, Dusseldorf, Amsterdam
2026 Sails: Apr 30, More...
AmaWaterways Cruise Tours, AmaStella Cruise Tours
AmaStella Cruise Tours18 Night - Magnificent Europe with Amsterdam Pre-Cruise and Budapest Post-Cruise
Starting in Amsterdam, Dusseldorf, Rudesheim, Wertheim, Wurzburg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: Apr 30, More...
Viking River, Viking Modi
Viking Modi Cruises10 Night - Rhine & Main Explorer
Starting in Basel, Breisach, Strasbourg, Karlsruhe, Frankfurt, Scenic Sailing Main River, Marktheidenfeld, Wurzburg, Bamberg, Nuremberg
2026 Sails: May 1, May 21, Jun 10, Jun 30, Jul 20, Aug 9, Aug 29, Sep 18, Oct 8, Oct 28, Nov 17, Dec 7, 2027: Jun 3, Jun 23, Jul 13, Aug 2, Aug 22, Sep 11, Oct 1, Oct 21, Nov 10, Nov 30, More...
Viking River, Viking Skirnir
Viking Skirnir Cruises10 Night - Rhine & Main Explorer
Starting in Nuremberg, Bamberg, Wurzburg, Marktheidenfeld, Scenic Sailing Main River, Frankfurt, Karlsruhe, Strasbourg, Breisach, Basel
2026 Sails: May 1, May 21, Jun 10, Jun 30, Jul 20, Aug 9, Aug 29, Sep 18, Oct 8, Oct 28, Nov 17, Dec 7, 2027: May 14, Jun 3, Jun 23, Jul 13, Aug 2, Aug 22, Sep 11, Oct 1, Oct 21, Nov 10, Nov 30, More...
AmaWaterways, AmaLea
AmaLea Cruises14 Night - Magnificent Europe
Starting in Budapest, Bratislava, Vienna, Durnstein, Melk, Linz, Engelhartszell, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Freudenberg, Rudesheim, Lahnstein, Dusseldorf, Amsterdam
2026 Sails: May 2, May 30, More...
AmaWaterways, AmaStella
AmaStella Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Dusseldorf, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 2, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: May 2, Jun 27, Aug 22, Sep 19, 2027: Apr 24, Sep 25, Oct 23, More...

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Main River Cruises