Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Aug 1, Sep 26, More...

Emerald Cruises, Emerald Astra

10 Night - Jewels of the Rhine & Glacier Express
Starting in Amsterdam (Huizen), Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim (Heidelberg), Kehl / Strasbourg, Breisach / Freiburg, Basel (Breisach) Zermatt, Zermatt, Zermatt / Zurich, Zurich
2026 Sails: Aug 1, More...

Amadeus River, MS Amadeus Amara

8 Night - German Riverscapes from Trier to Passau
Starting in Trier, Cochem, Koblenz, Miltenberg, Wurzburg, Zeil am Main, Nuremberg, Regensburg, Passau
2026 Sails: Aug 2, More...

AmaWaterways Tours, AmaPrima Tours

13 Night - Europe's Rivers & Castles (Wine Cruise) with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 2, 2027: Mar 21, May 2, Aug 8, Sep 19, More...

Uniworld, River Duchess

14 Night - European Jewels
Starting in Amsterdam, Cologne, Rudesheim, Frankfurt (Heidelberg), Wertheim, Wurzburg, Cruising the Main River, Kitzingen (Rothenburg), Bamberg, Nuremberg, Cruising the Main-Danube Canal, Regensburg, Passau, Weissenkirchen (Melk), Tulln, Vienna, Budapest
2026 Sails: Aug 2, Sep 13, Oct 11, More...

Uniworld Tours, River Duchess Tours

23 Night - Ultimate European Journey
Starting in Amsterdam, Cologne, Rudesheim, Frankfurt (Heidelberg), Wertheim, Wurzburg, Cruising the Main River, Kitzingen (Rothenburg), Bamberg, Nuremberg, Cruising the Main-Danube Canal, Regensburg, Passau, Weissenkirchen (Melk), Tulln, Vienna, Budapest, Batina (Osijek), Vukovar, Belgrade, Golubac, Cruising the Iron Gates, Vidin, Ruse, Giurgiu, Transfer to Bucharest, Bucharest
2026 Sails: Aug 2, More...

Avalon Waterways, Avalon Expression

14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Aug 4, Aug 20, Oct 16, More...

Avalon Waterways, Avalon Impression

Scenic Luxury, Scenic Jasper

14 Night - Jewels of Europe
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 4, Sep 1, More...

Scenic Luxury, Scenic Opal

14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Aug 4, More...

<= Back

More =>