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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Italy Coast : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury, Scenic Jasper
Scenic Jasper17 Night - Christmas Markets with Paris
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2027 Sails: Nov 23, 2028: Nov 24, More...
Scenic Luxury, Scenic Jasper
Scenic Jasper14 Night - Christmas Markets
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2027 Sails: Nov 23, 2028: Nov 24, More...
AmaWaterways, AmaCerto
AmaCerto7 Night - Magical Christmas Markets of Germany
Starting in Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Koblenz, Mainz, Frankfurt
2027 Sails: Nov 24, Dec 8, Dec 22, More...
Avalon Waterways, Avalon Expression
Avalon Expression15 Night - Christmastime from Basel to Vienna
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Excursion to Munich (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2027 Sails: Nov 25, More...
Avalon Waterways, Avalon Expression
Avalon Expression9 Night - Christmastime from Basel to Nuremberg
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2027 Sails: Nov 25, More...
Avalon Waterways, Avalon Expression
Avalon Expression4 Night - Christmastime in Alsace & Germany (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt (Disembarkation)
2027 Sails: Nov 25, More...
Avalon Waterways Tours, Avalon Expression Tours
Avalon Expression Tours11 Night - Christmastime from Basel to Nuremberg with in Prague
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2027 Sails: Nov 25, More...
Uniworld, S.S. Audrey
S.S. Audrey7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2027 Sails: Nov 25, Dec 9, 2028: Nov 25, Dec 9, More...
AmaWaterways Tours, AmaVenita Tours
AmaVenita Tours11 Night - Swiss Alps & Rhine Castles (Christmas) with Milan, Italy and Lake Como, Italy Pre-Cruise
Starting in Miltenberg, Laconia, Basel, Strasbourg, Ludwigshafen, Lahnstein, Cologne, Amsterdam
2027 Sails: Nov 26, Dec 10, More...
Avalon Waterways Tours, Avalon Envision Tours
Avalon Envision Tours11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2027 Sails: Nov 26, Dec 10, More...

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Main River Cruises