Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises5 Night - Christmastime in the Heart of Germany
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 11, More...
Avalon Waterways Cruise Tours, Avalon Illumination Cruise Tours
Avalon Illumination Cruises11 Night - Christmastime from Nuremberg to Basel with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 11, More...
Avalon Waterways Cruise Tours, Avalon Illumination Cruise Tours
Avalon Illumination Cruises7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 11, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination Cruises9 Night - Christmastime from Nuremberg to Basel
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 13, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination Cruises5 Night - Christmastime in the Heart of Germany
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 13, More...
Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours
Avalon Imagery II Cruises7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 14, More...
Uniworld Boutique River Cruise Collection, S.S. Emilie
S.S. Emilie Cruises7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Dec 15, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 16, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination Cruises4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 18, More...
Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper Cruises20 Night - Christmas & New Year with Paris & Prague
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Cruising Day, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Linz, Melk / Durnstein, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Dec 19, More...

<= Back
More =>

Main River Cruises