Clayton River Cruises

River Cruises that visit North America: United States: New York: Clayton

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Lake Ontario Cruises

Click on a cruise ship itinerary that visits Clayton (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Clayton), please visit: Cruise Search or try our Virtual Cruise Advisor™.

American Lines Tours, American Patriot Tours

8 Night - Great Lakes & Thousand Islands Cruise
Starting in Syracuse, NY, Oswego, NY / Day of Cruising, Clayton, NY, Day of Cruising, Ogdensburg, NY, Rochester, NY, Day of Cruising the Welland Canal, Buffalo, NY
2026 Sails: May 22, Jun 5, 2027: May 2, Jun 23, Aug 21, Oct 5, 2028: May 1, Jun 22, Aug 20, Oct 4, More...

American Cruise Lines, American Patriot

8 Night - Great Lakes & Thousand Islands Cruise
Starting in Buffalo, NY, Day of Cruising, Day of Cruising the Welland Canal, Rochester, NY, Clayton, NY, Day of Cruising, Ogdensburg, NY, Oswego, NY
2026 Sails: May 29, Aug 27, 2027: Jun 16, Aug 14, Sep 28, Oct 12, 2028: Jun 15, Aug 13, Sep 27, Oct 11, More...