Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
33 Night - Seattle to Miami
Starting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Sep 24, More...
10 Night - Baja Peninsula & Sea of Cortez
Starting in Los Angeles, California, Cabo San Lucas, Mexico, La Paz, Mexico, Loreto, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Sep 25, More...
16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
8 Night - Mexican Riviera
Starting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Sep 26, Oct 10, Oct 24, Nov 7, 2027: Jan 30, Feb 13, Feb 27, More...
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
19 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 28, More...24 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Sep 28, More...15 Night - Msc Grand Voyages
Starting in Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Oct 2, More...
8 Night - Mexican Riviera
Starting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Oct 3, More...
7 Night - Halloween On the High Seas Mexican Riviera Cruise from San Diego
Starting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Oct 3, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
33 Night - Seattle to MiamiStarting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Sep 24, More...
10 Night - Baja Peninsula & Sea of CortezStarting in Los Angeles, California, Cabo San Lucas, Mexico, La Paz, Mexico, Loreto, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Sep 25, More...
16 Night - Journeys - Panama CanalStarting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2026 Sails: Sep 26, More...
8 Night - Mexican RivieraStarting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Sep 26, Oct 10, Oct 24, Nov 7, 2027: Jan 30, Feb 13, Feb 27, More...
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
19 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Sep 28, More...
24 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Sep 28, More...
15 Night - Msc Grand VoyagesStarting in Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2026 Sails: Oct 2, More...
8 Night - Mexican RivieraStarting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Oct 3, More...
7 Night - Halloween On the High Seas Mexican Riviera Cruise from San DiegoStarting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Oct 3, More...
