New Orleans Cruise Departures
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Sep 25, Oct 18, 2028: May 30, More...
7 Night - Bahamas
Starting in New Orleans, La, Key West, FL, Celebration Key, the Bahamas, Nassau, Bahamas, New Orleans, La
2026 Sails: Sep 27, Oct 25, 2027: Jan 17, Jan 31, Mar 14, Apr 11, May 23, Jun 20, Aug 1, Aug 29, Oct 10, Nov 7, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 9, 2027: Feb 13, Oct 28, Nov 3, More...7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, Nov 9, More...
5 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Oct 12, Oct 17, Oct 26, Oct 31, Nov 9, Nov 14, Nov 23, Nov 28, Dec 7, Dec 12, Dec 21, 2027: Jan 4, Jan 9, Jan 18, Jan 23, Feb 1, Feb 6, Feb 15, Feb 20, Mar 1, Mar 6, Mar 15, Mar 20, Mar 29, More...8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, May 12, May 26, Sep 8, Nov 26, Dec 10, Dec 24, More...4 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, May 10, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Sep 22, Oct 10, Oct 27, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, More...7 Night - Western Caribbean
Starting in New Orleans, La, Isla Tropicale, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 1, Dec 27, 2027: Jan 3, Jan 10, Feb 7, Feb 21, Feb 28, Mar 7, Mar 28, Apr 4, Apr 18, Apr 25, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, More...
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Sep 25, Oct 18, 2028: May 30, More...
7 Night - BahamasStarting in New Orleans, La, Key West, FL, Celebration Key, the Bahamas, Nassau, Bahamas, New Orleans, La
2026 Sails: Sep 27, Oct 25, 2027: Jan 17, Jan 31, Mar 14, Apr 11, May 23, Jun 20, Aug 1, Aug 29, Oct 10, Nov 7, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 9, 2027: Feb 13, Oct 28, Nov 3, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, Nov 9, More...
5 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Oct 12, Oct 17, Oct 26, Oct 31, Nov 9, Nov 14, Nov 23, Nov 28, Dec 7, Dec 12, Dec 21, 2027: Jan 4, Jan 9, Jan 18, Jan 23, Feb 1, Feb 6, Feb 15, Feb 20, Mar 1, Mar 6, Mar 15, Mar 20, Mar 29, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, May 12, May 26, Sep 8, Nov 26, Dec 10, Dec 24, More...
4 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, May 10, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Sep 22, Oct 10, Oct 27, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Isla Tropicale, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 1, Dec 27, 2027: Jan 3, Jan 10, Feb 7, Feb 21, Feb 28, Mar 7, Mar 28, Apr 4, Apr 18, Apr 25, May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, More...
