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Santiago Cruise Departures

Cruises that depart from South America: Chile: Santiago

Cruises that visit Santiago

Click on a cruise ship itinerary sailing from Santiago (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santiago), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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Coral Princess Cruise Tours21 Night - Iguazu Falls Adventure Tour 1A Santiago (San Antonio), Chile to Rio De Janeiro, Brazil
Cruise first (16 days), followed by land (5 days) 4 Ports: Santiago (San Antonio), Chile; Punta Arenas, Chile; Ushuaia (Tierra del Fuego), Argentina; Cape Horn (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Falkland Islands (Stanley); Montevideo, Uruguay; Buenos Aires, Argentina 3 Land Destinations: Buenos Aires, Argentina; Iguazu Falls, Brazil; Rio De Janeiro, Brazil
2021 Sails: Jan 3, More...
Coral Princess Cruise Tours19 Night - Iguazu Falls Adventure Tour 1C Santiago (San Antonio), Chile to Rio De Janeiro, Brazil
Cruise first (14 days), followed by land (5 days) 6 Ports: Santiago (San Antonio), Chile; Puerto Montt, Chile; Amalia Glacier, Chile (Scenic Cruising); Punta Arenas, Chile; Ushuaia (Tierra del Fuego), Argentina; Cape Horn (Scenic Cruising); Falkland Islands (Stanley); Puerto Madryn, Argentina; Montevideo, Uruguay; Buenos Aires, Argentina ... View All Ports 3 Land Destinations: Buenos Aires, Argentina; Iguazu Falls, Brazil; Rio De Janeiro, Brazil
2021 Sails: Feb 4, Mar 4, More...
MS Roald Amundsen Cruises18 Night - Antarctica, Chilean Fjords and Falklands – Great Explorers and Wildlife 2021/22 Roundtrip from Santiago de Chile
Starting in Santiago de Chile, Flight to Punta Arenas; with stops in Patagonia; Drake Passage; Antarctica; The Falkland Islands; Punta Arenas; Flight to Santiago de Chile
2021 Sails: Nov 8, Dec 10, Dec 26, 2022: Jan 11, Jan 27, Feb 12, Feb 28, More...
MS Roald Amundsen Cruises18 Night - Antarctica, Chilean Fjords and Falklands - Great Explorers and Solar Eclipse Roundtrip from Santiago de Chile
Starting in Santiago de Chile, Flight to Punta Arenas; with stops in Antarctica; South Orkeny Islands; The Falkland Islands; Punta Arenas; Flight to Santiago de Chile
2021 Sails: Nov 24, More...
Diamond Princess Cruise Tours21 Night - Iguazu Falls Adventure Tour 1C from Santiago (San Antonio), Chile to Rio De Janeiro, Brazil
Cruise first (16 days), followed by land (5 days) 4 Ports: Santiago (San Antonio), Chile; Punta Arenas, Chile; Ushuaia (Tierra del Fuego), Argentina; Cape Horn (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Antarctic Peninsula (Scenic Cruising); Falkland Islands (Stanley); Montevideo, Uruguay; Buenos Aires, Argentina 3 Land Destinations: Buenos Aires, Argentina; Iguazu Falls, Brazil; Rio De Janeiro, Brazil
2022 Sails: Jan 20, More...
Scenic Eclipse Cruises19 Night - Patagonian Adventure with Antarctica in Depth: Santiago to Buenos Aires aboard Scenic Eclipse (Combo)
Starting in Santiago with stops in Torres del Paine National Park, El Calafate, Ushuaia, Antarctic Peninsula, Buenos Aires
2022 Sails: Jan 29, More...
Azamara Quest Cruise Ship21 Night - Fjords & Antarctica Voyage onboard Azamara Quest
Starting in Santiago with stops in Puerto Montt, Puerto Chacabuco, Chilean Fjords, Punta Arenas, Beagle Channel, Ushuaia, Antarctic Sound/Peninsula, Port Stanley, Puerto Madryn, Montevideo, Buenos Aires
2022 Sails: Feb 2, More...
Diamond Princess Cruise Tours19 Night - Iguazu Falls Adventure Tour 1B from Santiago (San Antonio), Chile to Rio De Janeiro, Brazil
Cruise first (14 days), followed by land (5 days) 6 Ports: Santiago (San Antonio), Chile; Puerto Montt, Chile; Amalia Glacier, Chile (Scenic Cruising); Punta Arenas, Chile; Ushuaia (Tierra del Fuego), Argentina; Cape Horn (Scenic Cruising); Falkland Islands (Stanley); Puerto Madryn, Argentina; Montevideo, Uruguay; Buenos Aires, Argentina; Buenos Aires, Argentina 3 Land Destinations: Buenos Aires, Argentina; Iguazu Falls, Brazil; Rio De Janeiro, Brazil
2022 Sails: Feb 19, More...
Scenic Eclipse Cruises25 Night - Patagonian Adventure with Antarctica, South Georgia & Falkland Islands: Santiago to Rio de Janeiro aboard Scenic Eclipse (Combo)
Starting in Santiago with stops in Torres del Paine National Park, El Calafate, Ushuaia, Antarctic Peninsula, South Georgia, Falkland Islands, Rio de Janeiro
2022 Sails: Mar 3, More...
MS Roald Amundsen Cruises19 Night - Antarctica, Patagonia, Chilean Fjords - Voyage of Discovery (Northbound) from Santiago de Chile to Valparaiso
Starting in Santiago de Chile, Flight to Punta Arenas; with stops in Antarctica; Chilean Fjords; Puerto Natales; Puerto Eden; Castro; Valparaíso, Chile
2022 Sails: Mar 16, More...


Santiago Cruise Departures

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