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Portland Cruise Departures

Cruises that depart from North America: United States: Oregon: Portland

Cruises that visit Portland

See all River Cruises that depart from Portland

Click on a cruise ship itinerary sailing from Portland (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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American Song Cruises7 Night - Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainer, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2021 Sails: Mar 28, May 2, May 16, May 30, Jun 13, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Oct 17, Oct 31, Nov 14, More...
American Melody Cruises4 Night - Highlights of the Columbia River Cruise Roundtrip from Portland, OR
Starting in Portland, OR; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA
2021 Sails: Apr 1, Apr 5, Apr 9, Jun 25, 2022: Mar 23, Mar 27, Mar 31, Apr 4, Apr 8, More...
Queen of the West Cruises7 Night - Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Ranier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2021 Sails: Apr 10, Apr 24, Jul 24, Aug 21, More...
American Song Cruises4 Night - Highlights of the Columbia River Cruise
Starting in Portland, Oregon; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA; Portland, OR
2021 Sails: Apr 11, Jun 27, More...
American Pride Cruises10 Night - Northwest Pioneers Cruise from Portland to Clarkston
Starting in Portland, OR; with stops in Astoria, OR; Mt. St. Helens, WA; Portland, OR; Stevenson, WA; Hood River, OR; The Dalles; Richland, WA; Pendleton, OR; Clarkston, WA
2021 Sails: Apr 13, Jun 29, More...
American Song Cruises10 Night - Northwest Pioneers Cruise from Portland to Clarkston
Starting in Portland, OR; with stops in Astoria, OR; Mt. St. Helens, WA; Portland, OR; Stevenson, WA; Hood River, OR; The Dalles; Richland, WA; Pendleton, OR; Clarkston, WA
2021 Sails: Apr 15, Jul 1, Sep 29, More...
American Harmony Cruises7 Night - Columbia and Snake River Cruise from Portland, OR to Clarkston, WA
Starting in Portland, OR; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA; The Dalles, OR; Pendleton, OR; Richland, WA; Clarkston, WA
2021 Sails: Apr 21, Apr 28, May 5, May 12, May 19, May 26, Jun 2, Jun 9, Jun 16, Jun 23, Jun 30, Jul 7, Jul 14, Jul 21, Jul 28, Aug 4, Aug 11, Aug 18, Aug 25, Sep 1, Sep 8, Sep 15, Sep 22, Sep 29, More...
American Melody Cruises7 Night - Columbia and Snake Rivers Cruise from Portland, OR to Clarkston, WA
Starting in Portland, OR; with stops in Astoria, OR; Mount St. Helens, The Dalles, OR; Pendleton, OR / Richland, WA; Clarkston, WA
2021 Sails: Apr 30, May 14, May 28, Jun 11, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, 2022: Apr 29, May 13, May 27, Jun 10, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Oct 14, More...
Independence Cruises7 Night - Maine Coast and Harbors Cruise Rountrip from Portland, ME
Starting in Portland, ME; with stops in Bar Harbor, ME; Castine / Belfast, ME; Camden, ME; Rockland, ME; Boothbay Harbor, ME; Bath, ME
2021 Sails: May 23, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, 2022: Mar 28, Jun 4, Jun 11, Jun 18, Jun 25, More...
Queen of the West Cruises4 Night - Highlights of the Columbia River Cruise roundtrip from Portland, OR
Starting from Portland, OR; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA
2021 Sails: Jun 5, Jun 9, Jun 14, Jun 18, Jun 22, Oct 16, Oct 20, Oct 24, Oct 28, More...


Portland Cruise Departures

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