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Portland Cruise Departures

Cruises that depart from North America: United States: Oregon: Portland

Cruises that visit Portland

See all River Cruises that depart from Portland

Click on a cruise ship itinerary sailing from Portland (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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S.S. Legacy Cruises7 Night Rivers of Wine & Culinary roundtrip from Portland, Oregon
Starting in Portland, Oregon; Astoria; Hood River/Columbia River Gorge National Scenic Area; Walla Walla, Washington; Red Mountain; The Dalles, Oregon; Willamette Valley; Portland, Oregon
2019 Sails: Nov 23, Nov 30, Dec 7, More...
American Song Cruises7 Nights Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainer, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2020 Sails: Mar 14, Apr 6, Apr 20, May 4, Jun 7, Jun 21, Jul 25, Aug 8, Aug 22, Oct 15, Oct 26, Nov 9, Nov 23, 2021: Mar 25, Mar 28, May 2, May 16, May 30, Jun 13, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, More...
Independence Cruises7 Night Maine Coast and Harbors Cruise roundtrip from Portland, Maine
Starting in Portland, Maine; with stops in Bar Harbor, Maine; Castine, Maine; Camden, Maine; Rockland Maine; Boothbay Harbor, Maine; Bath, Maine
2020 Sails: Mar 20, Jun 6, Jun 13, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, More...
Queen of the West Cruises7 Nights Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Ranier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2020 Sails: Mar 27, Apr 10, Apr 24, May 16, May 30, Jun 13, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 19, 2021: Apr 10, Apr 24, Jul 24, Aug 21, More...
Queen of the West Cruises4 Night Highlights of the Columbia River Cruise roundtrip from Portland, OR
Starting from Portland, OR; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA
2020 Sails: Apr 6, May 8, May 12, Jun 27, Jul 1, Oct 11, Oct 15, 2021: Jun 5, Jun 9, Jun 14, Jun 18, Jun 22, Oct 16, Oct 20, Oct 24, Oct 28, More...
American Pride Cruises7 Nights Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2020 Sails: Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, 2021: Apr 30, May 14, May 28, Jun 11, Jul 16, Jul 30, Aug 13, Aug 27, More...
American Pride Cruises10 Night Northwest Pioneers Cruise from Portland to Clarkston
Starting in Portland, OR; with stops in Astoria, OR; Mt. St. Helens, WA; Portland, OR; Stevenson, WA; Hood River, OR; The Dalles; Richland, WA; Pendleton, OR; Clarkston, WA
2020 Sails: Apr 16, May 6, 2021: Apr 13, Jun 29, More...
American Song Cruises10 Night Northwest Pioneers Cruise from Portland to Clarkston
Starting in Portland, OR; with stops in Astoria, OR; Mt. St. Helens, WA; Portland, OR; Stevenson, WA; Hood River, OR; The Dalles; Richland, WA; Pendleton, OR; Clarkston, WA
2020 Sails: May 21, Jul 8, Sep 5, Sep 25, 2021: Apr 15, Jul 1, Sep 29, More...
American Song Cruises4-Night Highlights of the Columbia River Cruise
Starting in Portland, Oregon; with stops in Astoria, OR; Mount St. Helens, WA; Stevenson, WA; Portland, OR
2021 Sails: Apr 11, Jun 27, More...

Portland Cruise Departures

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