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Minneapolis River Cruise Departures

River Cruises that depart from North America: United States: Minnesota: Minneapolis

Mississippi River Cruises

Click on a river cruise ship itinerary sailing from Minneapolis (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just Minneapolis), please visit: Cruise Search or try our Virtual Cruise Advisor™.



American Queen Cruises8 Night Upper Mississippi Mark Twain's Mississippi from Red Wing to Alton
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; Alton, IL
2019 Sails: Jul 28, More...
American Duchess Cruises8 Night Upper Mississippi River Heartland Heritage Cruise Roundtrip from St. Paul
Starting in St. Paul, MN; with stops in Dubuque, IA; Prairie du Chien, WI; La Crosse, WI; Winona, MN; Red Wing, MN; St. Paul MN
2019 Sails: Aug 11, More...
American Queen Cruises15 Night The Mighty Mississippi from Red Wing to New Orleans
Starting in Red Wing; with stops in Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Helena, AR; Vicksburg, MS; Natchez, MS; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Aug 11, More...
American Duchess Cruises22 Night The Mighty Mississippi River Cruise from St. Paul to New Orleans
Starting in St. Paul, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; Alton, IL; St. Louis, MO; Chester, IL; Cape Girardeau, MO; Paducah, KY; New Madrid, MO; Memphis, TN; Helena, AR; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans
2019 Sails: Aug 18, More...
Minneapolis River Cruise Departures
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