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Minneapolis River Cruise Departures

River Cruises that depart from North America: United States: Minnesota: Minneapolis

See all Cruises that depart from Minneapolis

Mississippi River Cruises

Click on a cruise ship itinerary sailing from Minneapolis (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Minneapolis), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


American Countess Cruises8 Night - Minneapolis (Red Wing) to St. Louis (Alton)
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis (Alton)
2022 Sails: Jul 18, Aug 1, 2023: Jul 10, Jul 24, More...
American Duchess Cruises8 Night - Minneapolis (Red Wing) to St. Louis (Alton)
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis (Alton)
2022 Sails: Jul 30, Sep 10, 2023: Aug 19, Sep 2, More...
American Queen Cruises8 Night - Minneapolis (Red Wing) to St. Louis (Alton)
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis (Alton)
2022 Sails: Aug 28, Oct 16, 2023: Jul 23, Aug 6, More...
American Queen Cruises15 Night - Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2022 Sails: Sep 11, 2023: Oct 1, More...
American Duchess Cruises15 Night - Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2022 Sails: Sep 24, 2023: Sep 16, More...
American Countess Cruises15 Night - Minneapolis (Red Wing) to New Orleans
Starting in Minneapolis, MN; with stops in Red Wing, MN; Winona, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; St. Louis, MO; Memphis, TN; Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Nottoway; New Orleans, LA
2022 Sails: Sep 26, 2023: Sep 4, More...

Minneapolis River Cruise Departures

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